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公开(公告)号:EP3416633A1
公开(公告)日:2018-12-26
申请号:EP17753711.5
申请日:2017-02-15
发明人: KOZIKOWSKI, Alan , SHEN, Sida , BERGMAN, Joel , GAISINA, Irina N.
IPC分类号: A61K31/16 , A61K31/165 , C07D215/02
CPC分类号: A61K31/4709 , A61K31/47 , A61K45/06 , C07D215/18 , C07D215/227 , C07D241/42 , C07D241/44 , C07D279/16 , Y02A50/411 , A61K2300/00
摘要: Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease, traumatic brain injury, stroke, malaria, an autoimmune disease, autism, and inflammation, also are disclosed.