公开(公告)号：EP3210021A1

公开(公告)日：2017-08-30

申请号：EP15853565.8

申请日：2015-10-22

申请人： The George Washington University A Congretionally Chartered Not-For-Profit Corp. ,  Astute Medical, Inc.

发明人： CHAWLA, Lakhmir S. ,  MCCAFFREY, Timothy A. ,  MCPHERSON, Paul ,  KAMPF, James Patrick

IPC分类号： G01N33/53 ,  G01N33/493

CPC分类号： C12Q1/6883 ,  C12Q2600/158 ,  G01N33/566 ,  G01N33/6893 ,  G01N33/84 ,  G01N2500/04 ,  G01N2800/06 ,  G01N2800/56

摘要： The invention relates to methods and kits for diagnosing and/or treating appendicitis in a subject, comprising performing one or more assays configured to detect one or more biomarkers on a body fluid sample obtained from the subject to provide one or more assay result(s) and correlating the assay result(s) to the occurrence or nonoccurrence of appendicitis in the subject or likelihood of the future outcome to the subject.

摘要翻译： 本发明涉及用于诊断和/或治疗受试者阑尾炎的方法和试剂盒，包括从所述受试者获得生物样品; 检测生物样品中至少三种或更多种生物标志物的RNA表达水平，并比较所述至少三种或更多种生物标志物与对照样品的表达水平，其中所述至少三种或更多种生物标志物的表达水平的增加或降低 与对照样品相比，表明阑尾炎。

公开(公告)号：EP3209804A1

公开(公告)日：2017-08-30

申请号：EP15853139.2

申请日：2015-10-22

申请人： The George Washington University A Congretionally Chartered Not-For-Profit Corp.

发明人： CHAWLA, Lakhmir S. ,  MCCAFFREY, Timothy A.

IPC分类号： C12Q1/68 ,  G01N33/49

CPC分类号： C12Q1/6883 ,  C12Q2600/158 ,  G01N33/566 ,  G01N33/6893 ,  G01N33/84 ,  G01N2500/04 ,  G01N2800/06 ,  G01N2800/56

摘要： The invention relates to methods and kits for diagnosing and/or treating appendicitis in a subject, comprising performing one or more assays configured to detect one or more biomarkers on a body fluid sample obtained from the subject to provide one or more assay result(s) and correlating the assay result(s) to the occurrence or nonoccurrence of appendicitis in the subject or likelihood of the future outcome to the subject.