专利检索 ap:("The Johns Hopkins University") AND inv:"MINN, Ii" 第 1 页

1.

发明公开
GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF 审中-公开

公开(公告)号：EP3411121A1

公开(公告)日：2018-12-12

申请号：EP17748283.3

申请日：2017-02-03

申请人： The Johns Hopkins University

发明人： LIU, Jun , HE, Qingli , POMPER, Martin, G. , MINN, Ii , YU, Biao , WANG, Qiaoling

IPC分类号： A61P35/00 , A61P37/06 , C07D493/22

CPC分类号： C07D493/22 , C07J73/003

摘要： Provided are compounds generated by conjugation of triptolide with glucose to form glucose-triptolide conjugates, provides compounds with effective anti -proliferative activity and improved tolerability as compared to naturally occurring triptolide compounds.