公开(公告)号：EP1768704B9

公开(公告)日：2013-01-02

申请号：EP05788432.2

申请日：2005-06-20

申请人： The Johns Hopkins University

发明人： POMPER, Martin, G. ,  BETTEGOWDA, Chetan ,  FOSS, Catherine ,  ZHOU, Shibin room 589 Cancer Research Bldg ,  KINZLER, Kenneth room 589 Cancer Research Bldg ,  VOGELSTEIN, Bert room 589 Cancer Research Bldg

IPC分类号： A61K49/00

CPC分类号： A61K51/1241 ,  A61K51/0491 ,  A61K51/1231

公开(公告)号：EP1768704A2

公开(公告)日：2007-04-04

申请号：EP05788432.2

申请日：2005-06-20

申请人： THE JOHNS HOPKINS UNIVERSITY

发明人： POMPER, Martin, G. ,  BETTEGOWDA, Chetan ,  FOSS, Catherine ,  ZHOU, Shibin room 589 Cancer Research Bldg ,  KINZLER, Kenneth room 589 Cancer Research Bldg ,  VOGELSTEIN, Bert room 589 Cancer Research Bldg

IPC分类号： A61K49/00

CPC分类号： A61K51/1241 ,  A61K51/0491 ,  A61K51/1231

摘要： The instant invention provides a method for diagnosing an infection in a subject by administering to the subject a compound suitable for imaging which binds to a thymidine kinase present in the infecting organism, and obtaining an image of the subject to determine the presence and location of the compound, wherein a localization of the compound is indicative that the subject has an infection.

公开(公告)号：EP1768704B1

公开(公告)日：2012-05-02

申请号：EP05788432.2

申请日：2005-06-20

申请人： The Johns Hopkins University

发明人： POMPER, Martin, G. ,  BETTEGOWDA, Chetan ,  FOSS, Catherine ,  ZHOU, Shibin room 589 Cancer Research Bldg ,  KINZLER, Kenneth room 589 Cancer Research Bldg ,  VOGELSTEIN, Bert room 589 Cancer Research Bldg

IPC分类号： A61K49/00

CPC分类号： A61K51/1241 ,  A61K51/0491 ,  A61K51/1231

摘要： The instant invention provides a method for diagnosing an infection in a subject by administering to the subject a compound suitable for imaging which binds to a thymidine kinase present in the infecting organism, and obtaining an image of the subject to determine the presence and location of the compound, wherein a localization of the compound is indicative that the subject has an infection.