公开(公告)号：EP1767639B1

公开(公告)日：2012-02-29

申请号：EP05743390.6

申请日：2005-05-30

申请人： The Kitasato Institute (formerly known as School Juridical Person Kitasato Gakuen) ,  National Institute of Advanced Industrial Science and Technology

发明人： ITO, Akira Res. Center for Biologicals, The K.I. ,  GOTANDA, Toru Res. Center for Biologicals, The K.I ,  KOBAYASHI, Shigeki ,  KUME, Katsumi Res. Center for Biologicals, The K.I ,  MATSUMURA, Takeshi AIST Hokkaido

IPC分类号： C12N15/30 ,  A01H5/00 ,  A61K39/012 ,  A61P33/02 ,  C12N5/10 ,  C12P21/02 ,  C07K14/44

CPC分类号： C07K14/44 ,  A61K39/015 ,  A61K2039/542 ,  C12N15/8258

摘要： Potato leaf transformed by a vector which expresses an immunogenic protein gene R7 originating in the second generation schizont of Leucocytozoon caulleryi is administered as an oral vaccine to chickens. As a result, the antibody titer of the chickens can be successfully elevated.

公开(公告)号：EP1767639A1

公开(公告)日：2007-03-28

申请号：EP05743390.6

申请日：2005-05-30

申请人： THE KITASATO INSTITUTE ,  National Institute of Advanced Industrial Science and Technology

发明人： ITO, Akira Res. Center for Biologicals, The K.I. ,  GOTANDA, Toru Res. Center for Biologicals, The K.I ,  KOBAYASHI, S. Res. Center for Biologicals, The K.I ,  KUME, Katsumi Res. Center for Biologicals, The K.I ,  MATSUMURA, Takeshi AIST Hokkaido

IPC分类号： C12N15/30 ,  A01H5/00 ,  A61K39/012 ,  A61P33/02 ,  C12N5/10 ,  C12P21/02 ,  C07K14/44

CPC分类号： C07K14/44 ,  A61K39/015 ,  A61K2039/542 ,  C12N15/8258

摘要： Leaves of potato plants transformed with a vector that expresses an R7 immunogenic protein gene derived from second-generation schizonts of Leucocytozoon caulleryi were administered to chickens as an oral vaccine. As a result, the present inventors succeeded in increasing the antibody titer of the chickens.

摘要翻译： 以表达来自白细胞介素的第二代裂殖体的R7免疫原性蛋白质基因的载体转化的马铃薯植株的叶作为口服疫苗施用于鸡。 结果，本发明人成功地提高了鸡的抗体滴度。