METHOD OF MAKING A SKIN CARE COMPOSITION
    5.
    发明公开
    METHOD OF MAKING A SKIN CARE COMPOSITION 审中-公开
    制备护肤组合物的方法

    公开(公告)号:EP3191192A1

    公开(公告)日:2017-07-19

    申请号:EP15767640.4

    申请日:2015-09-08

    IPC分类号: A61Q19/02

    摘要: A method of identifying a test agent as a skin tone agent. The method includes determining the level of high-mobility group protein B1 (HMGB1), messenger RNA associated with the expression and/or regulation of HMGB1 (HMGB1 mRNA), and/or micro-RNA associated with the expression and/or regulation of HMGB1 (HMGB1 miRNA) present in the test sample, and identifying the test agent as a skin tone agent when there is no increase in HMGB1 level, a downregulation in transcription of HMGB1 mRNA, and/or an upregulation of HMGB1 miRNA. The method also includes identifying a test agent as a skin tone agent when the test agent inhibits or prevents an increase in melanocyte dendricity and/or body size caused by HMGB1.

    摘要翻译: 一种将测试剂识别为肤色剂的方法。 该方法包括测定高迁移率族蛋白B1(HMGB1),与HMGB1表达和/或调节相关的信使RNA(HMGB1mRNA)和/或与HMGB1的表达和/或调节相关的微RNA的水平 (HMGB1 miRNA),并且当HMGB1水平不增加,HMGB1 mRNA转录下调和/或HMGB1 miRNA上调时,将测试剂鉴定为肤色剂。 该方法还包括当测试剂抑制或防止由HMGB1引起的黑素细胞树突和/或身体尺寸增加时,将测试剂鉴定为肤色剂。

    COSMETIC COMPOSITIONS AND METHODS FOR INHIBITING MELANIN SYNTHESIS
    6.
    发明公开
    COSMETIC COMPOSITIONS AND METHODS FOR INHIBITING MELANIN SYNTHESIS 审中-公开
    化妆品组合物和抑制黑素合成的方法

    公开(公告)号:EP3191074A1

    公开(公告)日:2017-07-19

    申请号:EP15766725.4

    申请日:2015-09-11

    摘要: A cosmetic composition suitable for topical application, for example, is provided. In some examples, the cosmetic composition may include bisabolol, undecylenoyl phenylalanine and/or hexyldecanol, and a material selected from the group consisting of ethyl palmitate, stearyl alcohol, bis (2-ethylhexyl) adipate, bis (2-ethylhexyl) maleate, 5-pentadecanol, 1-stearoyl-rac-glycerol, bis (2-ethylhexyl) sebacate, and mixtures thereof. A method of reducing the synthesis of melanin by using the cosmetic compositions is also disclosed herein.

    摘要翻译: 例如,提供了适用于局部应用的化妆品组合物。 在一些实例中,化妆品组合物可包含红没药醇,十一碳烯酰基苯丙氨酸和/或己基癸醇,以及选自棕榈酸乙酯,硬脂醇,己二酸双(2-乙基己基)酯,马来酸二(2-乙基己基)酯,马来酸二 - 十五烷醇,1-硬脂酰 - 外消旋 - 甘油,双(2-乙基己基)癸二酸酯及其混合物。 本文还公开了通过使用化妆品组合物来减少黑色素合成的方法。

    COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF FACIAL PORES
    8.
    发明公开
    COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF FACIAL PORES 有权
    ZUSAMMENSETZUNGEN UNDVERFAHREN ZUR VERBESSERUNG DER DARSTELLUNG VON GESICHTPOREN。

    公开(公告)号:EP2640345A2

    公开(公告)日:2013-09-25

    申请号:EP11791148.7

    申请日:2011-11-17

    摘要: A method of improving the appearance of facial pores is provided. The method includes the step of applying a composition having an effective amount of a material that regulates IL-1 and/or hyaluronic acid synthesis to an area of facial pores, wherein the composition is applied for a period of time sufficient for the material to improve the appearance of the facial pores. In some embodiments, the material that regulates IL-1 and/or hyaluronic acid synthesis is hexyldecanol. The method may also include the step of identifying facial pores on a facial skin surface.

    摘要翻译: 提供了改善面部毛孔外观的方法。 该方法包括将具有有效量的调节IL-1和/或透明质酸合成的材料的组合物施用于面孔的区域的步骤,其中将组合物施用足以使材料改善的时间 面部毛孔的外观。 在一些实施方案中,调节IL-1和/或透明质酸合成的材料是己基癸醇。 该方法还可以包括识别面部皮肤表面上的面部孔的步骤。