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1.发明公开Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection 审中-公开方法和组合物用于治疗炎性疾病，自身免疫性疾病和移植排斥反应的预防和治疗
公开(公告)号：EP2289499A3
公开(公告)日：2012-05-16
申请号：EP10012690.3
申请日：2002-11-01
发明人： David, Michael I.
IPC分类号： A61K31/05 , A61K31/085 , A61K31/09 , A61K31/7028 , A61P37/02 , A61P29/00 , A61P37/06 , A61P1/00 , A61P11/06
CPC分类号： A61K31/05 , A61K31/085 , A61K31/09 , A61K31/135 , A61K31/70 , A61K31/7028 , A61K31/704
摘要： The invention provides compounds and pharmaceutical compositions for use in the treatment of a disease selected from the group consisting of sepsis and multiple sclerosis (MS) by the administration to a subject in need thereof a pharmaceutically effective amount of a purified compound of any one of Formulae. The invention's compounds and pharmaceutical compositions are useful for the prevention, amelioration, and treatment of sepsis or multiple sclerosis (MS)
摘要翻译： 本发明提供了组合物和方法用于降低自身免疫疾病，炎症性疾病的一种或多种症状，和/或移植排斥反应，通过给予需要其的药学上有效量的式A-E中任一项的纯化的化合物的受试者。 本发明的方法可用于预防，改善和治疗自身免疫性疾病，炎性疾病，和/或移植排斥反应的有用的。
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2.发明授权Compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection 有权组合物用于治疗炎性疾病，自身免疫性疾病和移植排斥反应的预防和治疗
公开(公告)号：EP2060255B1
公开(公告)日：2013-06-05
申请号：EP09002359.9
申请日：2002-11-01
发明人： David, Michael I.
IPC分类号： A61K31/05 , A61K31/085 , A61K31/09 , A61K31/7028 , A61K31/135 , A61K31/70 , A61K31/704 , A61P37/02 , A61P29/00 , A61P37/06 , A61P1/00 , A61P11/06 , A61P31/00
CPC分类号： A61K31/05 , A61K31/085 , A61K31/09 , A61K31/135 , A61K31/70 , A61K31/7028 , A61K31/704
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3.发明公开Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection 审中-公开方法和组合物用于治疗炎性疾病，自身免疫性疾病和移植排斥反应的预防和治疗
公开(公告)号：EP2289499A2
公开(公告)日：2011-03-02
申请号：EP10012690.3
申请日：2002-11-01
发明人： David, Michael I.
IPC分类号： A61K31/05 , A61K31/085 , A61K31/09 , A61K31/7028 , A61P37/02 , A61P29/00 , A61P37/06 , A61P1/00 , A61P11/06
CPC分类号： A61K31/05 , A61K31/085 , A61K31/09 , A61K31/135 , A61K31/70 , A61K31/7028 , A61K31/704
摘要： The invention provides compounds and pharmaceutical compositions for use in the treatment of a disease selected from the group consisting of sepsis and multiple sclerosis (MS) by the administration to a subject in need thereof a pharmaceutically effective amount of a purified compound of any one of Formulae. The invention's compounds and pharmaceutical compositions are useful for the prevention, amelioration, and treatment of sepsis or multiple sclerosis (MS)
摘要翻译： 本发明提供了化合物及其药物组合物用于在疾病的选自由管理由...组成脓毒症和多发性硬化（MS）的，以在需要其的药学上有效量的式中的任一项的纯化的化合物的受试者中治疗选自以下 ， 本发明的化合物和药物组合物可用于预防，改善，和脓毒病的治疗或多发性硬化（MS）
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4.发明公开Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection 有权方法和组合物用于治疗炎性疾病，自身免疫性疾病和移植排斥反应的预防和治疗
公开(公告)号：EP2060255A3
公开(公告)日：2010-03-10
申请号：EP09002359.9
申请日：2002-11-01
发明人： David, Michael I.
IPC分类号： A61K31/05 , A61K31/085 , A61K31/09 , A61K31/7028 , A61P37/02 , A61P29/00 , A61P37/06 , A61P1/00 , A61P11/06
CPC分类号： A61K31/05 , A61K31/085 , A61K31/09 , A61K31/135 , A61K31/70 , A61K31/7028 , A61K31/704
摘要： The invention provides compositions and methods for reducing one or more symptoms of an autoimmune disease, inflammatory disease, and/or transplant rejection, by the administration to a subject in need thereof a pharmaceutically effective amount of a purified compound of any one of Formulae A-E. The invention's methods are useful for the prevention, amelioration, and treatment of autoimmune disease, inflammatory disease, and/or transplant rejection.
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