公开(公告)号：EP1917040A2

公开(公告)日：2008-05-07

申请号：EP06802155.9

申请日：2006-08-23

申请人： The Regents of the University of California ,  Beth Israel Deaconess Medical Center ,  Duke University ,  University of Alabama at Birmingham Research Foundation

发明人： KORBER, Bette, T. ,  PERKINS, Simon ,  BHATTACHARYA, Tanmoy ,  FISCHER, William, M. ,  THEILER, James ,  LETVIN, Norman ,  HAYNES, Barton, F. ,  HAHN, Beatrice, H. ,  YUSIM, Karina ,  KUIKEN, Carla

IPC分类号： A61K48/00

CPC分类号： A61K39/21 ,  A61K39/00 ,  A61K39/12 ,  C12N2740/16034

摘要： The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.

公开(公告)号：EP3526236A1

公开(公告)日：2019-08-21

申请号：EP17861431.9

申请日：2017-10-17

申请人： Beth Israel Deaconess Medical Center, Inc. ,  Triad National Security, LLC

发明人： BAROUCH, Dan, H. ,  BRICAULT, Christine ,  KORBER, Bette, T. ,  YUSIM, Karina

IPC分类号： C07K14/16 ,  C12N15/49 ,  C12N5/10 ,  A61K39/21