专利检索 ap:("The Regents of the University of Minnesota") AND inv:"KRASUTSKY, Pavel, A." 第 1 页

1.

发明公开
SELECTIVE OXIDATION OF TRITERPENES EMPLOYING TEMPO 审中-公开
标题翻译：三萜类化合物的选择性氧化节奏使用

公开(公告)号：EP1869062A1

公开(公告)日：2007-12-26

申请号：EP06740130.7

申请日：2006-03-29

申请人： The Regents of the University of Minnesota

发明人： KRASUTSKY, Pavel, A. , PUSHECHNIKOV, Alexei , SERGEEVA, Tatiana

IPC分类号： C07J63/00

CPC分类号： C07J63/008

摘要： The present invention provides a process of preparing betulin-28-aldehyde from betulin. The process includes contacting betulin with a compound of formula (I), e.g., TEMPO (2,2,6,6-tetramethylpiperidine 1-oxyl) for a period of time effective to provide betulin-28-aldehyde. The present invention also provides a process of preparing betulinic acid. The process includes contacting betulin with a composition that includes: sodium hypochlorite (NaOCl); sodium chlorite (NaClO2), potassium chlorite (KClO2), or a combination thereof; and a compound of formula (I), e.g., TEMPO (2,2,6,6-tetramethylpiperidine 1-oxyl); for a period of time effective to provide betulinic acid.