专利检索 ap:("The U.S.A. as represented by the Secretary, Department of Health AND Human Services") AND inv:"MACKALL, Crystal" 第 1 页

1.

发明授权
ALK ANTIBODIES, CONJUGATES, AND CHIMERIC ANTIGEN RECEPTORS, AND THEIR USE 有权

公开(公告)号：EP3066118B1

公开(公告)日：2020-01-08

申请号：EP14805427.3

申请日：2014-11-06

申请人： The U.S.A. as represented by the Secretary, Department of Health and Human Services

发明人： ORENTAS, Rimas , MACKALL, Crystal

IPC分类号： C07K14/725 , C07K16/30 , C07K16/46

2.

发明公开
ALK ANTIBODIES, CONJUGATES, AND CHIMERIC ANTIGEN RECEPTORS, AND THEIR USE 审中-公开
标题翻译： ALK抗体偶联物及其嵌合抗原受体及其用途

公开(公告)号：EP3066118A2

公开(公告)日：2016-09-14

申请号：EP14805427.3

申请日：2014-11-06

申请人： The U.S.A. as represented by the Secretary, Department of Health and Human Services

发明人： ORENTAS, Rimas , MACKALL, Crystal

IPC分类号： C07K14/725 , C07K16/30 , C07K16/46

摘要： Chimeric antigen receptors that specifically bind to anaplastic lymphoma kinase are disclosed. Nucleic acids, recombinant expression vectors, host cells, antibodies, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.