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公开(公告)号:EP4036238A1
公开(公告)日:2022-08-03
申请号:EP21153875.6
申请日:2021-01-27
IPC分类号: C12N15/85 , C12N15/861
摘要: The invention relates to synthetic super-enhancers activated by one or more transcription factors. In particular, the present invention describes synthetic super-enhancers that are activated by one or more transcription factors expressed in a target cell and used to express transgenes, such as adverse payloads, upon activation of the synthetic super-enhancer by the transcription factor(s).