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    THERAPEUTIC AGENT FOR ACCELERATION OF SPINAL NERVE REPAIR COMPRISING DESACYL GHRELIN OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT
    3.
    发明公开
    THERAPEUTIC AGENT FOR ACCELERATION OF SPINAL NERVE REPAIR COMPRISING DESACYL GHRELIN OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT 审中-公开
    治疗剂脊髓神经修复与去酰基生长素释放肽或其衍生物作为活性ACCELERATION

    公开(公告)号：EP2070549A1

    公开(公告)日：2009-06-17

    申请号：EP07792413.2

    申请日：2007-08-10

    申请人： University of Miyazaki ,  Asubio Pharma Co., Ltd. ,  Japan as represented by president of National Cardiovascular Center

    发明人： MURAKAMI, Noboru ,  NAKAHARA, Keiko ,  HASHIMOTO, Miho ,  HAYASHI, Yujiro ,  KANGAWA, Kenji

    IPC分类号： A61K45/00 ,  A61K38/00 ,  A61K38/22 ,  A61P25/00 ,  A61P43/00

    CPC分类号： A61K38/25

    摘要： The invention provides a spinal neuron damage treating agent for use in the treatment of spinal neuron damage, or an agent for promoting the proliferation of spinal neuronal cells in the culture of spinal neuronal cells, or an agent for promoting the regeneration of spinal nerves after transplantation of cultured spinal neuronal cells, and the like.
    The invention provides an agent that contains a substance that acts on a des-acyl ghrelin specific binding site or a pharmaceutically acceptable salt thereof, the agent being a spinal neuron damage treating agent for use in the treatment of spinal neuron damage, or an agent for promoting the proliferation of cultured spinal neuronal cells in the culture of spinal neuronal cells, or an agent for promoting the regeneration of spinal nerves after transplantation of cultured spinal neuronal cells, and the like.

    摘要翻译： 本发明提供一种脊髓神经损伤治疗剂用于治疗脊髓神经损伤，或用于宣传廷的试剂脊髓神经细胞时的脊髓神经细胞的培养物中增殖，或者用于促销廷的试剂移植后脊髓神经再生 的培养的脊髓神经细胞，和类似物。 本发明提供的试剂没有包含的物质确实作用于去酰基化的生长素释放肽特异性结合部位或其药学上可接受的盐，其中该物质以一个脊髓神经损伤治疗剂用于治疗脊髓神经损伤，或剂 促销婷培养的脊髓神经细胞的脊髓神经细胞时的培养物中增殖，或者用于促销廷的试剂脊髓神经培养的脊髓神经细胞移植后的再生，等。

    THERAPEUTIC AGENT FOR ACCELERATION OF SPINAL NERVE REPAIR COMPRISING GHRELIN, DERIVATIVE THEREOF OR SUBSTANCE CAPABLE OF ACTING ON GHS-R1a AS ACTIVE INGREDIENT
    4.
    发明公开
    THERAPEUTIC AGENT FOR ACCELERATION OF SPINAL NERVE REPAIR COMPRISING GHRELIN, DERIVATIVE THEREOF OR SUBSTANCE CAPABLE OF ACTING ON GHS-R1a AS ACTIVE INGREDIENT 审中-公开
    治疗剂SPINALNERVENREPARATUR与生长素，它们的衍生物或物质而对GHS-R1A为活动加速

    公开(公告)号：EP2052738A1

    公开(公告)日：2009-04-29

    申请号：EP07792417.3

    申请日：2007-08-10

    申请人： University of Miyazaki ,  Asubio Pharma Co., Ltd. ,  Japan as represented by president of National Cardiovascular Center

    发明人： MURAKAMI, Noboru ,  NAKAHARA, Keiko ,  HASHIMOTO, Miho ,  HAYASHI, Yujiro ,  KANGAWA, Kenji

    IPC分类号： A61K45/00 ,  A61K38/22 ,  A61P19/08 ,  A61P25/00 ,  A61P43/00

    CPC分类号： C07K14/60 ,  A61K38/00

    摘要： The invention provides a spinal neuron damage treating agent for use in the treatment of spinal neuron damage, or an agent for promoting the proliferation of spinal neuronal precursor cells in the culture of spinal neuronal precursor cells, or an agent for promoting the regeneration of spinal nerves after transplantation of cultured spinal neuronal precursor cells, and the like.
    The invention provides an agent that contains a substance (e.g., ghrelin) that acts on the growth hormone secretagogue-receptor as an active ingredient, the agent being a spinal neuron damage treating agent for use in the treatment of spinal neuron damage, or an agent for promoting the proliferation of cultured spinal neuronal precursor cells in the culture of spinal neuronal precursor cells, or an agent for promoting the regeneration of spinal nerves after transplantation of cultured spinal neuronal precursor cells, and the like.

    摘要翻译： 本发明提供一种脊髓神经损伤治疗剂，用于治疗脊髓神经损伤，或用于宣传廷的试剂脊髓神经前驱细胞的脊髓神经前驱细胞的培养物中增殖，或者用于促销廷的试剂脊髓神经再生的 培养的脊髓神经前驱细胞移植等之后。 本发明提供的试剂没有包含的物质（例如，生长素释放肽）做了生长激素促分泌素受体充当活性成分的，该试剂是一​​个脊髓神经损伤治疗剂的使用中的脊髓神经损伤的治疗，或代理 为促销婷培养的脊髓神经前驱细胞的脊髓神经前驱细胞的培养物中增殖，或者用于促销廷的试剂脊髓神经培养的脊髓神经前驱细胞移植后的再生，等。