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    A BIOSENSOR DEVICE TO TARGET ANALYTES IN SITU, IN VIVO, AND/OR IN REAL TIME, AND METHODS OF MAKING AND USING THE SAME
    4.
    发明公开
    A BIOSENSOR DEVICE TO TARGET ANALYTES IN SITU, IN VIVO, AND/OR IN REAL TIME, AND METHODS OF MAKING AND USING THE SAME 审中-公开
    一种生物传感器装置，用于分析原位分析，实时分析和/或实时分析，以及制备和使用相同分析方法

    公开(公告)号：EP2972333A1

    公开(公告)日：2016-01-20

    申请号：EP14779197.4

    申请日：2014-03-11

    申请人： The University of Toledo

    发明人： AGARWAL, Anand, K. ,  GOEL, Vijay, K. ,  KIM, Dong-Shik ,  YOON, Do-Young ,  LIN, Boren ,  FEYZIZARNAGH, Hamid

    IPC分类号： G01N33/50

    CPC分类号： A61B5/14735 ,  A61B5/14546 ,  A61B5/4547 ,  A61B2503/40 ,  A61B2562/125 ,  G01N27/3272 ,  G01N27/3276 ,  G01N33/5438 ,  G01N33/56911 ,  G01N33/56938 ,  Y02A50/52 ,  Y02A50/57

    摘要： A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The transducer component includes the electrode and microprocessor configured to screen noise and to pick up impedance change at a very low frequency range.

    摘要翻译： 用于实时检测目标分析物的生物传感器装置包括可操作地连接到适于解释和发送可检测信号的换能器组件的接收器组件。 受体组分包括能够检测并结合至少一种目标分析物的感测元件和自组装单层（SAM）层。 SAM层位于感测元件和电极之间并与感测元件和电极接触，使得感测元件在存在目标分析物时导致能够传输到电极的可检测信号。 换能器组件包括电极和微处理器，用于筛选噪声并在极低频率范围内提取阻抗变化。