-
1.发明授权METHODS FOR IDENTIFYING BIOMARKERS USEFUL IN DIAGNOSIS OF BIOLOGICAL STATES 有权一种用于识别的生物标志物健身诊断性生物态的
公开(公告)号：EP1934377B1
公开(公告)日：2012-03-07
申请号：EP06814191.0
申请日：2006-09-05
IPC分类号： C12Q1/68 , G01N33/53 , G01N33/574
CPC分类号： C12Q1/6883 , C12Q1/6809 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , G01N33/6842 , Y02A90/26
摘要： The present invention relates to methods and compositions for identifying biomarkers that indicate a biological state, in particular transcription factor biomarkers and genes that can be regulated by such transcription factor biomarkers. The invention also relates to identifying polymorphisms in such transcription factors and regulated genes indicative of the biological state. The biomarkers and polymorphisms identified find use in diagnostic and treatment approaches, e.g., some embodiments the invention provide methods and kits for detecting bronchogenic carcinoma and risks thereof.
-
2.发明授权METHODS FOR IDENTIFYING BIOMARKERS USEFUL IN DIAGNOSIS AND/OR TREATMENT OF BIOLOGICAL STATES 有权方法鉴定的生物标志，生物学疾病的诊断和/或治疗用途是
公开(公告)号：EP1940860B1
公开(公告)日：2012-08-08
申请号：EP06814192.8
申请日：2006-09-05
IPC分类号： C07H21/04 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6883 , C12Q1/6809 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , G01N33/6842 , Y02A90/26
摘要： The present invention relates to methods and compositions for identifying biomarkers that indicate a biological state, in particular transcription factor biomarkers and genes that can be regulated by such transcription factor biomarkers. The invention also relates to identifying polymorphisms in such transcription factors and regulated genes indicative of the biological state. The biomarkers and polymorphisms identified find use in diagnostic and treatment approaches, e.g., some embodiments the invention provide methods and kits for detecting bronchogenic carcinoma and risks thereof.
-
公开(公告)号：EP3351661A1
公开(公告)日：2018-07-25
申请号：EP18159851.7
申请日：2013-11-25
CPC分类号： C12Q1/6806 , C12Q1/6851 , C12Q1/6869 , C40B20/04 , C12Q2545/107 , C12Q2535/122
摘要： Methods for standardized sequencing of nucleic acids and uses thereof are described.
A method for controlling for non-systematic error in an amplification-based next generation sequencing (NGS) library preparation, comprises:
including of an internal amplification control (IAC) sharing identical priming sites to a native nucleic acid target template of interest in a NGS library preparation;
mimicing the kinetics of the native nucleic acid target in the amplification reaction, and
controlling for sample-, platform-, experiment-, operator- and/or target-specific variation in amplification efficiency.-
4.发明公开METHODS AND COMPOSITIONS FOR IDENTIFYING BIOMARKERS USEFUL IN DIAGNOSIS AND/OR TREATMENT OF BIOLOGICAL STATES 有权方法鉴定的生物标志，生物学疾病的诊断和/或治疗用途是
公开(公告)号：EP1940860A2
公开(公告)日：2008-07-09
申请号：EP06814192.8
申请日：2006-09-05
IPC分类号： C07H21/04 , C12Q1/68 , G01N33/574
CPC分类号： C12Q1/6883 , C12Q1/6809 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , G01N33/6842 , Y02A90/26
摘要： The present invention relates to methods and compositions for identifying biomarkers that indicate a biological state, in particular transcription factor biomarkers and genes that can be regulated by such transcription factor biomarkers. The invention also relates to identifying polymorphisms in such transcription factors and regulated genes indicative of the biological state. The biomarkers and polymorphisms identified find use in diagnostic and treatment approaches, e.g., some embodiments the invention provide methods and kits for detecting bronchogenic carcinoma and risks thereof.
-
公开(公告)号：EP4025701A2
公开(公告)日：2022-07-13
申请号：EP20859812.8
申请日：2020-09-08
发明人： WILLEY, James, C. , CRAIG, Daniel, J. , BLOMQUIST, Thomas, M. , CRAWFORD, Erin, L. , YEO, Ji-Youn
IPC分类号： C12P19/34 , C12Q1/68 , C12Q1/6806 , C12Q1/6809 , C12Q1/6844 , C12Q1/6848
-
公开(公告)号：EP2922989A1
公开(公告)日：2015-09-30
申请号：EP13857053.6
申请日：2013-11-25
IPC分类号： C40B20/04
CPC分类号： C40B20/04 , C12Q1/6869 , C12Q2545/107 , C12Q2535/122
摘要： Methods for standardized sequencing of nucleic acids and uses thereof are described. The identification of genetic information is becoming a key piece of information for the diagnosis and treatment of many diseases. In order to make such diagnostic tool readily available, it is desired that this identification be as efficient and as inexpensive as possible.
-
7.发明公开
公开(公告)号：EP1934377A2
公开(公告)日：2008-06-25
申请号：EP06814191.0
申请日：2006-09-05
CPC分类号： C12Q1/6883 , C12Q1/6809 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/16 , G01N33/6842 , Y02A90/26
摘要： The present invention relates to methods and compositions for identifying biomarkers that indicate a biological state, in particular transcription factor biomarkers and genes that can be regulated by such transcription factor biomarkers. The invention also relates to identifying polymorphisms in such transcription factors and regulated genes indicative of the biological state. The biomarkers and polymorphisms identified find use in diagnostic and treatment approaches, e.g., some embodiments the invention provide methods and kits for detecting bronchogenic carcinoma and risks thereof.
-
公开(公告)号：EP2922989B1
公开(公告)日：2018-04-04
申请号：EP13857053.6
申请日：2013-11-25
CPC分类号： C12Q1/6806 , C12Q1/6851 , C12Q1/6869 , C40B20/04 , C12Q2545/107 , C12Q2535/122
摘要： Methods for standardized sequencing of nucleic acids and uses thereof are described. A method for controlling for non-systematic error in an amplification-based next generation sequencing (NGS) library preparation, comprises: including of an internal amplification control (IAC) sharing identical priming sites to a native nucleic acid target template of interest in a NGS library preparation; mimicing the kinetics of the native nucleic acid target in the amplification reaction, and controlling for sample-, platform-, experiment-, operator- and/or target-specific variation in amplification efficiency.
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.015 秒)
