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公开(公告)号：EP1869037A1
公开(公告)日：2007-12-26
申请号：EP06708816.1
申请日：2006-03-27
发明人： SIMMEN, Kenneth Alan , CHAKRAVARTY, Sarvajit , HART, Barry , SURLERAUX, Dominique Louis Nestor Ghislain , LIN, Tse-I , LENZ, Oliver , RABOISSON, Pierre, Jean-Marie, Bernard
IPC分类号： C07D471/04 , A61K31/495 , A61P31/00
CPC分类号： C07D471/04 , A61K31/495
摘要： Fused bicyclic pyrimidine compounds having an amide-substituted pyridylamine group at C-4 of the pyrimidine of formula (I) ring are useftul in the treatment of conditions associated with HCV.
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2.发明公开
公开(公告)号：EP1881834A1
公开(公告)日：2008-01-30
申请号：EP06777220.2
申请日：2006-05-12
发明人： RABOISSON, Pierre Jean-Marie Bernard , SURLERAUX, Dominique Louis Nestor Ghislain , LIN, Tse-I , LENZ, Oliver , SIMMEN, Kenneth Alan
IPC分类号： A61K31/519 , A61P31/14 , C07D475/10
CPC分类号： C07D475/10 , A61K31/519 , A61K31/5377 , A61K45/06 , C07D487/04 , Y02A50/385 , Y02A50/387 , A61K2300/00
摘要： The present invention relates to the use of pteridines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to compounds per se and their use as medicines. The present invention also concerns processes for the preparation of such compounds, pharmaceutical compositions comprising them, and combinations of said compounds with other anti-HCV agents.
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3.发明公开CARBOXAMIDE 4-[(4-PYRIDYL)AMINO] PYRIMIDINES FOR THE TREATMENT OF HEPATITIS C 有权甲酰胺4 - [（4-吡啶基）氨基]嘧啶类用于治疗丙型肝炎
公开(公告)号：EP2097084A2
公开(公告)日：2009-09-09
申请号：EP07820916.0
申请日：2007-10-04
IPC分类号： A61K31/506 , A61P31/14
CPC分类号： A61K31/506 , A61K31/535 , A61K2300/00
摘要： The present invention relates to the use of carboxamide 4-[(4-pyridyl)amino]-pyrimidines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections.
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4.发明公开PYRIDO[2,3-D]PYRIMIDINES USEFUL AS HCV INHIBITORS, AND METHODS FOR THE PREPARATION THEREOF 有权吡啶并[2,3-D]嘧啶类引致的，HCV抑制剂SUITABLE AND METHOD FOR THEIR
公开(公告)号：EP1888580A2
公开(公告)日：2008-02-20
申请号：EP06763142.4
申请日：2006-05-12
发明人： SIMMEN, Kenneth Alan , SURLERAUX, Dominique Louis Nestor Ghislain , LIN, Tse-I , LENZ, Oliver , RABOISSON, Pierre Jean-Marie Bernard
IPC分类号： C07D471/04 , A61K31/519 , A61P31/14
CPC分类号： C07D471/04 , A61K31/519
摘要： The present invention relates to the use of pyrido[2,3-d]pyrimidines as inhibitors of 10 HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to pyrido- [2,3-d]pyrimidines co mpounds per se and their use as medicines. The present invention also concerns processes for the preparation of such compounds, pharmaceut ical compositions co mprising them, and combinations of said compounds 15 with other anti-HCV agents.
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公开(公告)号：EP1799218A1
公开(公告)日：2007-06-27
申请号：EP05789523.7
申请日：2005-09-29
发明人： SIMMEN, Kenneth Alan , LIN, Tse-I , LENZ, Oliver , SURLERAUX, Dominique, Louis, Nestor, Ghislain , RABOISSON, Pierre, Jean-Marie, Bernard
IPC分类号： A61K31/517 , A61K31/519 , A61K31/52 , A61K31/53 , A61K31/5377 , A61P1/16 , A61P31/14 , A61P35/00
CPC分类号： A61K31/517 , A61K31/519 , A61K31/52 , A61K31/53 , A61K31/5377 , Y02A50/385 , Y02A50/387
摘要： The present invention relates to the use of bi-cyclic pyrimidines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to processes for preparation of such pharmaceutical compositions. The present invention also concerns combinations of the present bi-cyclic pyrimidines with other anti-HCV agents.
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