公开(公告)号：EP1597238B1

公开(公告)日：2007-05-09

申请号：EP04737252.9

申请日：2004-02-20

申请人： Tibotec Pharmaceuticals Ltd.

发明人： GUILLEMONT, Jerôme, Emile, Georges ,  PASQUIER, Elisabeth, Thérese, Jeanne ,  HEERES, Jan ,  HERTOGS, Kurt ,  BETTENS, Eva ,  LEWI, Paulus, Joannes ,  DE JONGE, Marc, René ,  KOYMANS, Lucien, Maria, Henricus ,  DAEYAERT, Frederik, Frans, Desiré ,  VINKERS, Hendrik, Maarten ,  JANSSEN, Paul, Adriaan, Jan DI

IPC分类号： C07D239/47 ,  A61K31/505 ,  C07D239/48 ,  C07D407/12 ,  A61P31/18

CPC分类号： C07D239/47 ,  C07D239/48 ,  C07D413/12

摘要： This invention concerns HIV replication inhibitors of formula (I), The N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.

公开(公告)号：EP1603887A1

公开(公告)日：2005-12-14

申请号：EP04737251.1

申请日：2004-02-20

申请人： Tibotec Pharmaceuticals Ltd.

发明人： GUILLEMONT, Jerôme, Emile, Georges ,  PASQUIER, Elisabeth, Thérese, Jeanne ,  HEERES, Jan ,  HERTOGS, Kurt ,  BETTENS, Eva ,  LEWI, Paulus, Joannes ,  DE JONGE, Marc, René ,  KOYMANS, Lucien, Maria, Henricus ,  DAEYAERT, Frederik, Frans, Desiré ,  VINKERS, Hendrik, Maarten ,  JANSSEN, Paul, Adriaan, Jan DI

IPC分类号： C07D239/47 ,  A61K31/505 ,  C07D239/48 ,  C07D413/12 ,  A61P31/18

CPC分类号： C07D239/47 ,  C07D239/48 ,  C07D413/12

摘要： This invention concerns HIV replication inhibitors of formula (I), the N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.

公开(公告)号：EP1597238A1

公开(公告)日：2005-11-23

申请号：EP04737252.9

申请日：2004-02-20

申请人： Tibotec Pharmaceuticals Ltd.

发明人： GUILLEMONT, Jerôme, Emile, Georges ,  PASQUIER, Elisabeth, Thérese, Jeanne ,  HEERES, Jan ,  HERTOGS, Kurt ,  BETTENS, Eva ,  LEWI, Paulus, Joannes ,  DE JONGE, Marc, René ,  KOYMANS, Lucien, Maria, Henricus ,  DAEYAERT, Frederik, Frans, Desiré ,  VINKERS, Hendrik, Maarten ,  JANSSEN, Paul, Adriaan, Jan DI

IPC分类号： C07D239/47 ,  A61K31/505 ,  C07D239/48 ,  C07D407/12 ,  A61P31/18

CPC分类号： C07D239/47 ,  C07D239/48 ,  C07D413/12

摘要： This invention concerns HIV replication inhibitors of formula (I), The N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.