专利检索 ap:("Tina Holding ApS") AND inv:"FILICHEV, Vyachelsav V." 第 1 页

1.

发明授权
STABLE AND SELECTIVE FORMATION OF HOOGSTEEN-TYPE TRIPLEXES AND DUPLEXES USING TWISTED INTERCALATING NUCLEIC ACIDS (TINA) AND PROCESS FOR THE PREPARATION OF TINA 有权
标题翻译：霍氏TYPE稳定和有选择性的培训和三层复式使用TINA（扭转嵌入核酸）及其制造方法蒂娜

公开(公告)号：EP1888748B1

公开(公告)日：2013-08-28

申请号：EP06753367.9

申请日：2006-05-24

申请人： Tina Holding ApS

发明人： FILICHEV, Vyachelsav V. , PEDERSEN, Erik Bjerregaard

IPC分类号： C12N15/11 , C07H21/00

CPC分类号： C12N15/111 , C07H21/00 , C12N2310/15 , C12N2310/332 , C12N2310/3511

2.

发明公开
STABLE AND SELECTIVE FORMATION OF HOOGSTEEN-TYPE TRIPLEXES AND DUPLEXES USING TWISTED INTERCALATING NUCLEIC ACIDS (TINA) AND PROCESS FOR THE PREPARATION OF TINA 有权
标题翻译：霍氏TYPE稳定和有选择性的培训和三层复式使用TINA（扭转嵌入核酸）及其制造方法蒂娜

公开(公告)号：EP1888748A2

公开(公告)日：2008-02-20

申请号：EP06753367.9

申请日：2006-05-24

申请人： Tina Holding ApS

发明人： FILICHEV, Vyachelsav V. , PEDERSEN, Erik Bjerregaard

IPC分类号： C12N15/11 , C07H21/00

CPC分类号： C12N15/111 , C07H21/00 , C12N2310/15 , C12N2310/332 , C12N2310/3511

摘要： The present invention describes a flexible basestacking monomer that can be incorporated into an oligonucleotide or oligonucleotide analogue, as well as triplex forming oligonucleotides comprising the flexible basestacking monomer. Triplex forming oligonucleotides of the invention are capable of binding sequence specifically to doublestranded target nucleic acids and are therefore of interest for modulation of the activity of target nucleic acids and also detection of target nucleic acids.