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    METHOD OF ANALYSIS FOR MUCIN 1 HAVING SUGAR CHAIN OF Sia 2-8Sia 2-3Gal -R
    1.
    发明公开
    METHOD OF ANALYSIS FOR MUCIN 1 HAVING SUGAR CHAIN OF Sia 2-8Sia 2-3Gal -R 有权
    具有Sia 2-8Sia 2-3Gal-R的糖链的粘蛋白1的分析方法

    公开(公告)号：EP2568286A1

    公开(公告)日：2013-03-13

    申请号：EP11777474.5

    申请日：2011-05-06

    申请人： Tokyo Institute of Technology ,  Yamaguchi University

    发明人： YAMASHITA Katsuko ,  FUKUSHIMA Keiko ,  HINODA Yuji

    IPC分类号： G01N33/53 ,  G01N33/574

    CPC分类号： G01N33/6893 ,  G01N33/57415 ,  G01N2333/4725

    摘要： The object of the present invention is to provide a clinical marker capable of distinguishing breast cancer from interstitial pneumonia; and a clinical marker for detecting malignancy or progress level of breast cancer, and for monitoring effects of the treatment of breast cancer. The object can be solved by a method for analyzing mucin 1 having Siaα2-8Siaα2-3Galβ-R, characterized by comprising the step of bringing a first probe specifically binding to a mucin 1 having Siaα2-8Siaα2-3Galβ-R into contact with a sample to be tested.

    摘要翻译： 本发明的目的是提供一种能区分乳腺癌和间质性肺炎的临床标志物; 以及用于检测乳腺癌的恶性程度或进展水平的临床标志物以及用于监测乳腺癌治疗效果的临床标志物。 该目的可以通过分析具有Siaα2-8Siaα2-3Galβ-R的粘蛋白1的方法来解决，其特征在于包括以下步骤：使与Siaα2-8Siaα2-3Galβ-R的粘蛋白1特异性结合的第一探针与样品接触 进行测试。

    METHOD FOR ANALYZING PSA, AND METHOD FOR DISTINGUISHING BETWEEN PROSTATE CANCER AND PROSTATOMEGALY EMPLOYING THE ANALYSIS METHOD
    2.
    发明公开
    METHOD FOR ANALYZING PSA, AND METHOD FOR DISTINGUISHING BETWEEN PROSTATE CANCER AND PROSTATOMEGALY EMPLOYING THE ANALYSIS METHOD 有权
    用于分析和方法的PSA过程中的前列腺癌以及分析方法的基础前列腺肥大区分

    公开(公告)号：EP2395357A1

    公开(公告)日：2011-12-14

    申请号：EP10738595.7

    申请日：2010-02-04

    申请人： Tokyo Institute of Technology ,  GP Biosciences Ltd.

    发明人： YAMASHITA Katsuko ,  FUKUSHIMA Keiko ,  BABA Shiro ,  SATOH Takefumi

    IPC分类号： G01N33/574

    CPC分类号： G01N33/57434 ,  G01N2333/4724 ,  G01N2800/342

    摘要： A method for distinguishing prostate cancer from prostatic hypertrophy using the method for analyzing PSA and an analysis kit of PSA are provided.
    An object of the present invention can be solved by being brought into contact a lectin having an affinity for β-N-acetylgalactosamine residues and/or a lectin having an affinity for fucose α(1, 2) galactose residues with a sample possibly containing PSA, to determine an amount of PSA having an affinity for the lectin. A method for distinguishing prostate cancer from prostatic hypertrophy can be provided by this method.

    摘要翻译： 提供了一种用于使用该方法用于分析PSA和PSA的分析试剂盒，从前列腺肥大区分前列腺癌的方法。 本发明的目的可以通过被接触具有亲和性的凝集素为²-N-乙酰残基和/或具有至亲和力与岩藻糖±凝集素可以解决（1，2）半乳糖残基与样品可能含有PSA ，确定性矿量的具有为外源凝集素亲和PSA的。 可以通过这种方法来提供一种用于从前列腺肥大区分前列腺癌的方法。