公开(公告)号：EP2659914B1

公开(公告)日：2020-06-24

申请号：EP11854069.9

申请日：2011-12-27

申请人： Toray Industries, Inc.

发明人： UENO, Yoshiyuki ,  FUJITA, Masaki ,  SUGAYA, Hiroyuki ,  HASHIMOTO, Kazuyuki ,  TERASAKA, Hiroyuki ,  KOGANEMARU, Ryo

IPC分类号： A61L33/00 ,  A61M1/18 ,  B01D63/02 ,  B01D65/08 ,  B01D67/00

公开(公告)号：EP2659914A1

公开(公告)日：2013-11-06

申请号：EP11854069.9

申请日：2011-12-27

申请人： Toray Industries, Inc.

发明人： UENO, Yoshiyuki ,  FUJITA, Masaki ,  SUGAYA, Hiroyuki ,  HASHIMOTO, Kazuyuki ,  TERASAKA, Hiroyuki ,  KOGANEMARU, Ryo

IPC分类号： A61L33/00 ,  A61M1/18 ,  B01D63/02

摘要： The purpose of the invention of the present application is to provide a medical material and a blood purification apparatus each having high anti-thrombotic properties and high safety. The apparatus is produced by incorporating therein a medical material which has a hydrophilic copolymerization polymer present on a surface thereof which is to be in contact with blood, wherein particulate protuberances each having a particle diameter of 50 nm or more are present on the surface which is to be in contact with blood at a density of 3 particles/µm 2 or less and the relaxation time of adsorbed water in the hydrophilic copolymerization polymer is 2.5 × 10 -8 seconds or shorter and 5.0 × 10 -10 seconds or longer at -40°C.

摘要翻译： 本发明的目的在于提供一种具有高抗血栓性和高安全性的医用材料和血液净化装置。 该装置通过在其中加入具有在其与血液接触的表面上存在的亲水性共聚聚合物的医疗材料来制造，其中在表面上存在粒径为50nm以上的颗粒状突起， 以3个/μm2以下的密度与血液接触，亲水性共聚聚合物中吸附水的松弛时间为2.5×10 -8秒以下，在-40℃下为5.0×10 -10秒以上 C。