公开(公告)号：EP3954377A1

公开(公告)日：2022-02-16

申请号：EP21167921.2

申请日：2015-07-03

申请人： Transimmune AG ,  Yale University

发明人： Bauer, Günter ,  Duckworth, Justin ,  Tigelaar, Robert ,  Edelson, Richard ,  Girardi, Michael ,  Henco, Karsten ,  Hayday, Adrian

IPC分类号： A61K35/15 ,  C12N5/0784 ,  A61P35/00

摘要： The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.

公开(公告)号：EP3741843A1

公开(公告)日：2020-11-25

申请号：EP20160435.2

申请日：2014-01-02

申请人： Transimmune AG ,  Yale University

发明人： Henco, Karsten ,  Bauer, Günter ,  Duckworth, Justin ,  Hayday, Adrian ,  Edelson, Richard ,  Tigelaar, Robert ,  Girardi, Michael

IPC分类号： C12N5/0784 ,  A61K35/15

摘要： The present invention relates to methods for producing immuno-stimulatory autologous dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from hyper-proliferative disease such as cancer.

公开(公告)号：EP3719118A1

公开(公告)日：2020-10-07

申请号：EP20160436.0

申请日：2014-01-02

申请人： Transimmune AG ,  Yale University

发明人： Henco, Karsten ,  Bauer, Günter ,  Duckworth, Justin ,  Hayday, Adrian ,  Edelson, Richard ,  Tigelaar, Robert ,  Girardi, Michael

IPC分类号： C12N5/0784 ,  A61K35/15

摘要： The present invention relates to methods for producing immuno-suppressive dendritic cells. The present invention further relates to the use of such cells for treating patients suffering from autoimmune diseases, hypersensitivity diseases, rejection on solid-organ transplantation and/or Graft-versus-Host disease.