公开(公告)号：EP4216680A1

公开(公告)日：2023-07-26

申请号：EP22207642.4

申请日：2013-04-25

申请人： Triumf Inc.

发明人： SCHAFFER, Paul ,  BENARD, Francois ,  BUCKLEY, Kenneth R. ,  HANEMAAYER, Victoire ,  KLUG, Julius Alexander ,  KOVACS, Michael S. ,  MORLEY, Thomas J. ,  RUTH, Thomas J ,  VALLIANT, John ,  ZEISLER, Stefan K. ,  DODD, Maurice G. ,  MANUELA, Cornelia Hoehr

IPC分类号： H05H6/00 ,  G21G1/10 ,  C22B5/18 ,  C22B34/30 ,  C22B9/14 ,  C25D13/02 ,  G21K5/08 ,  C25D13/22 ,  B22F9/22

摘要： A process for producing technetium-99m from a molybendum-100 metal powder, comprising the steps of: (i) irradiating in a substantially oxygen-free environment, a hardened sintered target plate coating with a Mo-100 metal, with protons produced by a cyclotron; (ii) dissolving molybdenum ions and technetium ions from the irradiated target plate with an H 2 O 2 solution to form an oxide solution; (iv) raising the pH of the oxide solution to about 14; (v) flowing the pH-adjusted oxide solution through a resin column to immobilize K[TcO 4 ] ions therefrom; (vi) eluting the bound K[TcO 4 ] ions from the resin column; (vii) flowing the eluted K[TcO 4 ] ions through an alumina column to immobilize K[TcO 4 ] ions thereon; (viii) washing the immobilized K[TcO 4 ] ions with water; (ix) eluting the immobilized K[TcO 4 ] ions with a saline solution; and (x) recovering the eluted Na[TcO 4 ] ions.

公开(公告)号：EP4110768A1

公开(公告)日：2023-01-04

申请号：EP21760355.4

申请日：2021-02-25

申请人： Triumf Inc. ,  Provincial Health Services Authority ,  The University of British Columbia

发明人： YANG, Hua ,  GAO, Feng ,  SCHAFFER, Paul ,  YUAN, Zheliang ,  ZHANG, Chengcheng ,  BENARD, Francois ,  WHARTON, Luke

IPC分类号： C07D273/00 ,  A61K51/04 ,  A61K51/08 ,  A61K51/10