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公开(公告)号：EP1005540B1
公开(公告)日：2004-06-16
申请号：EP98933095.6
申请日：1998-07-01
申请人： Tularik Inc.
发明人： GOEDDEL, David, V. , WORONICZ, John
CPC分类号： C12N9/1205 , A61K38/00
摘要： The invention provides methods and compositions relating to an IλB kinase, IKK-β, and related nucleic acids. The polypeptides may be produced recombinantly from transformed host cells from the disclosed IKK-β encoding nucleic acids or purified from human cells. The invention provides isolated IKK-β hybridization probes and primers capable of specifically hybridizing with the disclosed IKK-β genes, IKK-β-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
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公开(公告)号：EP1005540A1
公开(公告)日：2000-06-07
申请号：EP98933095.6
申请日：1998-07-01
申请人： TULARIK, INC.
发明人： GOEDDEL, David, V. , WORONICZ, John
CPC分类号： C12N9/1205 , A61K38/00
摘要： The invention provides methods and compositions relating to an IλB kinase, IKK-β, and related nucleic acids. The polypeptides may be produced recombinantly from transformed host cells from the disclosed IKK-β encoding nucleic acids or purified from human cells. The invention provides isolated IKK-β hybridization probes and primers capable of specifically hybridizing with the disclosed IKK-β genes, IKK-β-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
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