专利检索 ap:("UCB, S.A.") AND inv:"DIOUF, Ousmane" 第 1 页

1.

发明公开
PROCESS FOR PREPARING 2-OXO-1-PYRROLIDINE DERIVATIVES 有权
标题翻译：制备2-氧代-1-吡咯烷衍生物

公开(公告)号：EP1667967A1

公开(公告)日：2006-06-14

申请号：EP04765134.4

申请日：2004-09-13

申请人： UCB, S.A.

发明人： SURTEES, John , LURQUIN, Françoise , DIOUF, Ousmane

IPC分类号： C07D207/26

CPC分类号： C07D207/277 , C07D207/267

摘要： The present invention relates to a new process for preparing 2-oxo- I -pyrrolidine derivatives of general formula (I) wherein the substituents are as defined in the specification.

2.

发明公开
PROCESS FOR THE PREPARATION OF 2-(2-(4-(BIS(4-FLUOROPHENYL)METHYL)-PIPERAZIN-1-YL)ETHOXY)ACETIC ACID DERIVATIVES OR CORRESPONDING SALT FORMS THEREOF AND INTERMEDIATES THEREFOR 审中-公开
标题翻译：工艺用于制备2-（2-（4-（双（4-氟苯基））哌嗪-1-基）乙氧基）乙酸衍生物或类似的盐形态及其中间体

公开(公告)号：EP1414460A1

公开(公告)日：2004-05-06

申请号：EP02758376.4

申请日：2002-07-22

申请人： UCB, S.A.

发明人： DIOUF, Ousmane , SURTEES, John

IPC分类号： A61K31/495 , C07D295/088

CPC分类号： C07D295/088 , A61K31/495

摘要： The present invention relates to a process for the manufacture of 2-{2-[4-(bis(4-fluorophenyl)methyl)-1-piperazinyl]ethoxy}acetic acids, amides or related derivatives, of the general formula (I) wherein: Y represents hydroxy or -NR1R2; R1 and R2 each independently represent hydrogen or C?1-4#191 alkyl; m is 1 or 2, and n is 1 or 2, as well as the non-toxic, pharmaceutically acceptable salts and mixtures thereof. The present invention concerns also a polymorphic form of efletirizine.