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公开(公告)号：EP2346878B1
公开(公告)日：2014-10-01
申请号：EP09740187.1
申请日：2009-10-21
申请人： UCB Pharma, S.A.
IPC分类号： C07D495/04 , A61P29/00 , A61K31/4365
CPC分类号： C07D495/04
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公开(公告)号：EP2346878A1
公开(公告)日：2011-07-27
申请号：EP09740187.1
申请日：2009-10-21
申请人： UCB Pharma, S.A.
IPC分类号： C07D495/04 , A61P29/00 , A61K31/4365
CPC分类号： C07D495/04
摘要： A series of heteroaryl-substituted fused pyridine derivatives, in particular heteroaryl-substituted thieno[3,2-6]pyridine derivatives, being selective inhibitors of PO kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
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公开(公告)号：EP2231641A2
公开(公告)日：2010-09-29
申请号：EP08865707.7
申请日：2008-12-17
申请人： UCB Pharma, S.A.
发明人： ALLEN, Daniel, Rees , BUCKLEY, George, Martin , BÜRLI, Roland , DAVENPORT, Richard, John , KINSELLA, Natasha , LOCK, Christopher, James , LOWE, Christopher , MACK, Stephen, Robert , PITT, William, Ross , RATCLIFFE, Andrew, James , RICHARD, Marianna, Dilani , SABIN, Verity, Margaret , SHARPE, Andrew , TAIT, Laura, Jane , WARRELOW, Graham, John , WILLIAMS, Sophie, Caroline
IPC分类号： C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14 , C07D409/14 , C07D413/14 , C07D473/34 , C07D473/36 , A61K31/395 , A61P35/00
CPC分类号： C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14 , C07D409/14 , C07D413/14 , C07D473/34 , C07D473/36
摘要： A series of heteroaryl-substituted quinoxaline and quinoline derivatives, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
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