专利检索 ap:("UNIV CORNELL") AND inv:"MOHAMMED FARHEEN SULTANA" 第 1 页

1.

发明公开
EFFICIENT SYNTHESIS OF NICOTINAMIDE MONONUCLEOTIDE 审中-公开

公开(公告)号：EP3274357A4

公开(公告)日：2018-01-31

申请号：EP16773806

申请日：2016-03-24

申请人： UNIV CORNELL

发明人： SAUVE ANTHONY , MOHAMMED FARHEEN SULTANA

IPC分类号： C07H1/02 , A61K31/7028 , A61K31/7032 , C07H19/048

CPC分类号： C07H19/048 , C07H1/02

摘要： The invention provides a process for the preparation of nicotinamide mononucleotide having formula (I): The method involves the protection of nicotinamide riboside by ketalization, followed by phosphorylation and then deprotection to provide nicotinamide mononucleotide.

2.

发明公开
SYNTHESES, ACTIVITIES, AND METHODS OF USE OF DIHYDRONICOTINAMIDE RIBOSIDE DERIVATIVES 审中-公开

公开(公告)号：EP3322419A4

公开(公告)日：2018-08-01

申请号：EP16825278

申请日：2016-07-15

申请人： UNIV CORNELL

发明人： SAUVE ANTHONY , MOHAMMED FARHEEN SULTANA , YANG YUE

IPC分类号： C07H19/04 , A61K31/7052 , C07H1/00 , C07H19/048

CPC分类号： C07H19/048 , A23L33/10 , A23V2002/00 , C07H1/00 , C07H1/06 , C07H19/04

摘要： wherein R1, R2, R3, and are as defined herein. Also disclosed are methods for increasing mammalian cell NAD+ production and improving mitochondrial cell densities comprising administering to a cell the compound or a salt thereof.