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1.发明公开METHOD FOR ALLEVIATING SIDE EFFECTS OF RETINOIC ACID THERAPY AND/OR IMPROVING EFFICACY WITHOUT INTERFERING WITH EFFICACY 有权FOR浮雕 - 视黄酸治疗的副作用的方法和/或增加的效率，而不会影响有效性
公开(公告)号：EP2120917A4
公开(公告)日：2011-09-14
申请号：EP08726182
申请日：2008-02-27
IPC分类号： A61K31/21 , A61K8/36 , A61K8/49 , A61K31/203 , A61K31/455 , A61P17/00 , A61Q17/00
CPC分类号： A61K31/455 , A61K8/671 , A61K8/675 , A61K31/203 , A61K2800/75 , A61K2800/88 , A61K2800/884 , A61Q19/00 , A61K2300/00
摘要： The invention relates to the use of nicotinic acid alkyl esters, especially myristyl nicotinate, to inhibit side effects associated with retinoic acid therapy. Also a part of the invention is a method for improving skin cell differentiation by administering the nicotinic acid alkyl ester in an amount sufficient to increase expression of caspase 14 and filaggrin. Deficiencies in expression of these molecules can be treated in this way as well.
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2.发明公开METHOD FOR TREATING HAIR GROWTH DISORDERS, SUCH AS FEMALE PATTERN ALOPECIA, AND COMPOSITIONS USEFUL THEREFORE 有权方法对头发的生长问题的处理，如 女脱发和有用的组合物中
公开(公告)号：EP1898867A4
公开(公告)日：2011-04-27
申请号：EP06774072
申请日：2006-06-26
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