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公开(公告)号:EP1181277A4
公开(公告)日:2005-08-10
申请号:EP01920835
申请日:2001-03-28
申请人: UNIV MICHIGAN STATE
发明人: HOLLINGSWORTH RAWLE I , PISTIA-BRUEGGEMAN GABRIELA
IPC分类号: C07D211/46 , C07D211/76 , C07H7/027 , C07D211/36 , C07H5/04 , C07H5/06 , C07H15/00
CPC分类号: C07D211/76 , C07D211/46
摘要: A process for the preparation of 1,5-dideoxy-1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.