MICROCAVITY BIOSENSOR, METHODS OF MAKING, AND USES THEREOF
    1.
    发明公开
    MICROCAVITY BIOSENSOR, METHODS OF MAKING, AND USES THEREOF 有权
    MIKROKAVITÄTSBIOSENSOR,HERSTELLUNGSVERFAHREN UND VERWENDUNGEN DAVON

    公开(公告)号:EP1373894A4

    公开(公告)日:2004-04-21

    申请号:EP02706399

    申请日:2002-02-21

    申请人: UNIV ROCHESTER

    摘要: A biological sensor which includes: a porous semiconductor structure comprising a central layer interposed between upper and lower layers, each of the upper and lower layers including strata of alternating porosity; and one or more probes coupled to the porous semiconductor structure, the one or more probes binding to a target molecule, whereby a detectable change occurs in a refractive index of the biological sensor upon binding of the one or more probes to the target molecule. Methods of making the biological sensor and methods of using the same are disclosed, as is a detection device which includes such a biological sensor.

    摘要翻译: 一种生物传感器,其包括:多孔半导体结构,其包括置于上层和下层之间的中心层,所述上层和下层中的每一层包括交替孔隙的层; 以及一个或多个与所述多孔半导体结构偶联的探针,所述一个或多个探针结合于靶分子,由此当所述一个或多个探针结合至所述靶分子时,所述生物传感器的折射率发生可检测的变化。 公开了制造生物传感器的方法及其使用方法,以及包括这种生物传感器的检测装置。