专利检索 ap:("UNIVERSITY OF VIRGINIA PATENT FOUNDATION") AND inv:"CARTER, Karen, M." 第 1 页

1.

发明公开
VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS 审中-公开
标题翻译： VINYLPHOSPHONAT-LYSOPHOSPHATIDSÄURE-REZEPTORANTAGONISTEN

公开(公告)号：EP2054424A1

公开(公告)日：2009-05-06

申请号：EP07813308.9

申请日：2007-07-24

申请人： UNIVERSITY OF VIRGINIA PATENT FOUNDATION

发明人： CARTER, Karen, M. , LYNCH, Kevin, R. , MACDONALD, Timothy, L.

IPC分类号： C07F9/58 , A61K31/662 , A61P9/00 , A61P29/00 , A61P35/00

CPC分类号： C07F9/582

摘要： The present invention provides LPA analogs that are antagonists at the LPA receptors. The analogs have the formula (I) wherein Z is -CY=CH- or -G≡C-; wherein when Z is -CY=CH- then the double bond is in the trans (e) configuration; Y is hydrogen or halogen, and R1-R° and m and n are as defined in the application.