公开(公告)号：EP2046295A1

公开(公告)日：2009-04-15

申请号：EP07766448.0

申请日：2007-07-13

申请人： Unilever PLC

发明人： Elphick, Andrew James ,  Staniforth, John ,  Wang, Dong ,  Duncalf, David John ,  Rannard, Steven Paul ,  Long, James ,  Foster, Alison Jayne

IPC分类号： A61K9/16 ,  A61K31/167 ,  A61K31/192 ,  A61K31/60

摘要： A process for the production of a composition comprising a water-insoluble paracetamol or NSAID which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble paracetamol or NSAID, ii) a water soluble carrier, and iii) a solvent for each of the paracetamol or NSAID and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the paracetamol or NSAID in the carrier.

公开(公告)号：EP2046296A2

公开(公告)日：2009-04-15

申请号：EP07766449.8

申请日：2007-07-13

申请人： Unilever PLC

发明人： Duncalf, David John ,  Rannard, Steven Paul ,  Long, James ,  Wang, Dong ,  Elphick, Andrew James ,  Staniforth, John ,  Foster, Alison Jayne

IPC分类号： A61K9/16 ,  A61K31/167 ,  A61K31/192 ,  A61K31/60

摘要： A process for the production of a composition comprising a water-insoluble triptan which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble triptan, ii) a water soluble carrier, and iii) a solvent for each of the triptan and the carrier, and b) spray-drying the mixture to remove the or each solvent and obtain a substantially solvent-free nano-dispersion of the triptan in the carrier.