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    PROCESS OF MANUFACTURE OF AN ANTIPERSPIRANT COMPOSITION
    1.
    发明公开
    PROCESS OF MANUFACTURE OF AN ANTIPERSPIRANT COMPOSITION 审中-公开
    制备抗过敏剂组合物的方法

    公开(公告)号：EP3220878A1

    公开(公告)日：2017-09-27

    申请号：EP15794159.2

    申请日：2015-11-11

    申请人： Unilever PLC ,  Unilever NV

    发明人： FRANKLIN, Kevin, Ronald ,  KASTRINAKIS, Anestis ,  LUCKWELL, Craig, James ,  WATERFIELD, Philip, Christopher

    IPC分类号： A61K8/26 ,  A61Q15/00

    CPC分类号： A61K8/26 ,  A61K8/062 ,  A61K8/20 ,  A61K8/34 ,  A61K8/44 ,  A61Q15/00

    摘要： A process for manufacture of an antiperspirant composition comprising the reaction of an aqueous solution of aluminium sesquichlorohydrate, water soluble calcium salt and amino acid, at a total anhydrous solids content of from 33 to 60% by weight and at a temperature of at least 65° C., for a period of from 1 to 24 hours, wherein the molar ratio of water soluble calcium salt to aluminium sesquichlorohydrate is at least 1:40 and the molar ratio of amino acid to aluminium sesquichlorohydrate is at least 1:20, the mixture then being cooled to less than 25° C. and diluted with at least an equal weight of water or to a total anhydrous solids content of less than 31% by weight, the dilution phase being performed within 10 days of cooling phase.

    摘要翻译： 一种制造止汗剂组合物的方法，该方法包括使三水合氯化铝的水溶液，水溶性钙盐和氨基酸反应，总无水固体含量为33-60重量％，温度至少为65℃ 其中水溶性钙盐与倍半氯化铝水合物的摩尔比为至少1:40，氨基酸与倍半氯化氢铝的摩尔比为至少1:20，然后混合物 冷却至低于25℃并用至少等重量的水稀释或稀释至小于31重量％的总无水固体含量，稀释相在冷却阶段的10天内进行。