-
1.发明公开THE PROCESS FOR THE EXPRESSION AND PRODUCTION OF THE RECOMBINANT HUMAN BETA-CIS INTERFERON 失效方法表达和重组生产，人力BETA-CIS干扰素
公开(公告)号：EP0963437A1
公开(公告)日：1999-12-15
申请号：EP97953597.0
申请日：1997-12-19
发明人： PEREGRINO FERREIRA, Paulo Cesar , GEESSIEN KROON, Erna , GOLGHER, Romain, Rolland , BONJARDIM, Cláudio, Antonio , DE CARVALHO, Alex, Fiorini
CPC分类号： C07K14/565 , A61K38/00 , Y02A50/473
摘要： The invention provides a new human interferon (IFN)-beta variant cloned from an amniotic cell library, a cDNA encoding it, and processes for its production and purification. The variant, termed interferon beta-cis, differs from previously known hIFN-beta isoforms by the substitution of a Cys residue for the Tyr present at position 60. Recombinant IFN beta-cis exhibits antiviral activity characteristic of IFN-beta.
-
2.发明授权THE PROCESS FOR THE EXPRESSION AND PRODUCTION OF THE RECOMBINANT HUMAN BETA-CIS INTERFERON 失效方法表达和重组生产，人力BETA-CIS干扰素
公开(公告)号：EP0963437B1
公开(公告)日：2005-10-26
申请号：EP97953597.8
申请日：1997-12-19
发明人： PEREGRINO FERREIRA, Paulo Cesar , GEESSIEN KROON, Erna , GOLGHER, Romain, Rolland , BONJARDIM, Cláudio, Antonio , DE CARVALHO, Alex, Fiorini
IPC分类号： C12N15/22
CPC分类号： C07K14/565 , A61K38/00 , Y02A50/473
摘要： The invention provides a new human interferon (IFN)-beta variant cloned from an amniotic cell library, a cDNA encoding it, and processes for its production and purification. The variant, termed interferon beta-cis, differs from previously known hIFN-beta isoforms by the substitution of a Cys residue for the Tyr present at position 60. Recombinant IFN beta-cis exhibits antiviral activity characteristic of IFN-beta.
-
搜索结果
2 条记录 (耗时 0.009 秒)
