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1.发明授权PULSED BIO-AGENT DELIVERY SYSTEMS BASED ON IN VIVO DEGRADABLE AND SWELLABLE MODIFIED DEXTRAN HYDROGELS 有权在体内可降解改性可膨胀DEXTRANHYDROGELEN为基础的系统冲击WAY RELEASE生理活性物质
公开(公告)号：EP1455832B1
公开(公告)日：2008-02-20
申请号：EP02790247.7
申请日：2002-12-20
申请人： Universiteit Gent
CPC分类号： A61K9/0019 , A61K9/1652 , A61K9/205 , A61K47/36 , C08L5/02
摘要： A degradable oligomer or polymer aqueous solution or a degradable polymer hydrogel, wherein degradation occurs by cleavage of the oligomer or polymer backbone and/or, in the case of a hydrogel, by cleavage of cross-linking bonds within the hydrogel, is useful as a component of a time-controlled explosion bio-agent release system or a pulsed bio-agent delivery system comprising at least one biologically active agent and an outer semi-permeable lipid or polymer membrane, wherein bio-agent release or delivery begins after a lag time.
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2.发明公开PULSED BIO-AGENT DELIVERY SYSTEMS BASED ON DEGRADABLE POLYMER SOLUTIONS OR HYDROGELS 有权在体内可降解改性可膨胀DEXTRANHYDROGELEN为基础的系统冲击WAY RELEASE生理活性物质
公开(公告)号：EP1455832A2
公开(公告)日：2004-09-15
申请号：EP02790247.7
申请日：2002-12-20
申请人： UNIVERSITEIT GENT
CPC分类号： A61K9/0019 , A61K9/1652 , A61K9/205 , A61K47/36 , C08L5/02
摘要： A degradable oligomer or polymer aqueous solution or a degradable polymer hydrogel, wherein degradation occurs by cleavage of the oligomer or polymer backbone and/or, in the case of a hydrogel, by cleavage of cross-linking bonds within the hydrogel, is useful as a component of a time-controlled explosion bio-agent release system or a pulsed bio-agent delivery system comprising at least one biologically active agent and an outer semi-permeable lipid or polymer membrane, wherein bio-agent release or delivery begins after a lag time.
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