专利检索 ap:("University College Cork-National University of Ireland, Cork" OR "TEAGASC, The Agriculture AND Food Development Authority") AND inv:"FIELD, Des" 第 1 页

1.

发明公开
VARIANT NISIN PEPTIDES 审中-公开

公开(公告)号：EP3822285A1

公开(公告)日：2021-05-19

申请号：EP19208735.1

申请日：2019-11-12

申请人： University College Cork-National University of Ireland, Cork , TEAGASC, The Agriculture and Food Development Authority

发明人： COTTER, Paul , SHEEHAN, Diarmuid , BHAGYA JONNALA, Rekha , FIELD, Des , HILL, Colin , ROSS, Paul

IPC分类号： C07K14/315 , A23L3/3526 , A61K38/16

摘要： The invention relates to a variant nisin peptide, wherein the variant nisin peptide is a modified variant of wild-type nisin, wherein the modification comprises or consists of an amino acid residue modification selected from: i) M17Q or M17A; ii) T2L; and iii) one set of modified hinge residues selected from a) N20H and M21T, b) N20V, M21G, and K22A, c) N20V, M21G, and K22V or d) N20V, M21G, and K22T; or v) combinations of modifications i), ii), and iii), and related medical uses and products comprising such nisin peptides.