公开(公告)号：EP3368068B1

公开(公告)日：2020-11-18

申请号：EP16801955.2

申请日：2016-10-28

申请人： University of Copenhagen

发明人： BERTELSEN, Adam Frederik Sander ,  SALANTI, Ali ,  THEANDER, Thor ,  THRANE, Susan ,  MIKKEL JANITZEK, Christoph ,  ØRSKOV AGERBÆK, Mette ,  AGERTOUG NIELSEN, Morten

IPC分类号： A61K39/00 ,  A61K39/015 ,  C12N7/00

公开(公告)号：EP3368068A1

公开(公告)日：2018-09-05

申请号：EP16801955.2

申请日：2016-10-28

申请人： The University of Copenhagen

发明人： FREDERIK SANDER PEDERSEN, Adam ,  SALANTI, Ali ,  THEANDER, Thor ,  THRANE, Susan ,  MIKKEL JANITZEK, Christoph ,  ØRSKOV AGERBÆK, Mette ,  AGERTOUG NIELSEN, Morten

IPC分类号： A61K39/00 ,  A61K39/015 ,  C12N7/00

摘要： The invention relates to a virus like particle (VLP) based vaccine. The virus-like particle constitutes a non-naturally occurring, ordered and repetitive antigen array display scaffold which can obtain a strong and long-lasting immune response in a subject. The VLP based vaccine may be used for the prophylaxis and/or treatment of a disease including, but is not limited to, cancer, cardiovascular, infectious, asthma, and/or allergy diseases/disorders.

公开(公告)号：EP3244915A1

公开(公告)日：2017-11-22

申请号：EP16703049.3

申请日：2016-01-15

申请人： University of Copenhagen

发明人： PEDERSEN, Adam, Frederik, Sander ,  SALANTI, Ali ,  THEANDER, Thor ,  THRANE, Susan ,  JANITZEK, Christoph, Mikkel ,  ØRSKOV AGERBÆK, Mette ,  AGERTOUG NIELSEN, Morten ,  TOBIAS GUSTAFSSON, Jan

IPC分类号： A61K39/00 ,  A61K39/385 ,  C07K14/315

CPC分类号： A61K39/0011 ,  A61K39/00 ,  A61K39/385 ,  A61K2039/5258 ,  A61K2039/55516 ,  A61K2039/6068 ,  A61K2039/6075 ,  A61K2039/627 ,  A61P35/00 ,  C07K14/005 ,  C07K2319/735 ,  C12N2795/00023 ,  C12N2795/00034 ,  C12N2795/00071

摘要： The invention relates to a virus-like particle (VLP) based vaccine. The virus-like particle constitutes a non-naturally occurring, ordered and repetitive antigen array display scaffold which can obtain a strong and long-lasting immune response in a subject. The VLP-based vaccine may be used for the prophylaxis and/or treatment of a disease including, but is not limited to, cancer, cardiovascular, infectious, chronic, neurological diseases/disorders, asthma, and/or immune-inflammatory diseases/disorders.