专利检索 ap:("University of Maryland at Baltimore County") AND inv:"CREIGHTON, Donald" 第 1 页

1.

发明公开
COMPETITIVE INHIBITORS OF GLYOXALASE I AND METHOD OF GENERATING SUCH COMPETITIVE INHIBITORS INSIDE TUMOR CELLS 审中-公开
标题翻译：竞争性抑制剂乙二醛酶I AND METHOD FOR RELEASE在肿瘤细胞中，这种竞争性抑制剂

公开(公告)号：EP1051396A1

公开(公告)日：2000-11-15

申请号：EP99900776.8

申请日：1999-01-07

申请人： University of Maryland at Baltimore County

发明人： CREIGHTON, Donald , HAMILTON, Diana, S. , KAVARANA, Malcolm, J.

IPC分类号： C07C333/00

CPC分类号： C07C381/14 , C07C333/04 , C07C333/08

摘要： The present invention provides a compound having structure (I) wherein S* is S=O or O=S=O; and wherein R1 is selected from the group consisting of (C1-C9) alkyl, (C3-C8) cycloalkyl, (C5-C7) cycloalkenyl, and (C6-C20) aryl substituted with halogen or (C1-C18) alkyl; and wherein R2 is selected from the group consisting of alkyl, (C1-C9) alkyl, (C3-C8) cycloalkyl, (C5-C7) cycloalkenyl, and (C6-C20) aryl substituted with hologen or (C1-C18) alkyl. Also provided are various methods of using the compositions of the present invention.