公开(公告)号：EP2900674A1

公开(公告)日：2015-08-05

申请号：EP13774891.9

申请日：2013-09-27

申请人： University of Washington through its Center for Commercialization ,  Fred Hutchinson Cancer Research Center

发明人： RUBEL, Edwin ,  SIMON, Julian ,  CHEN, Xinchao ,  CHOWDHURY, Sarwat ,  HERR, R., Jason ,  JIANG, Qin ,  OWENS, Kelly, N. ,  RAIBLE, David ,  JOHNSON, Graham

IPC分类号： C07D495/04 ,  A61K31/407

CPC分类号： C07D495/04 ,  A61K31/4365 ,  A61K31/439 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/70 ,  A61K45/06 ,  C07D495/08 ,  C07D495/18

摘要： Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing, treating, and/or protecting against sensory hair cell death. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.

公开(公告)号：EP2900674B1

公开(公告)日：2017-05-31

申请号：EP13774891.9

申请日：2013-09-27

申请人： University of Washington through its Center for Commercialization ,  Fred Hutchinson Cancer Research Center

发明人： RUBEL, Edwin ,  SIMON, Julian ,  CHEN, Xinchao ,  CHOWDHURY, Sarwat ,  HERR, R., Jason ,  JIANG, Qin ,  OWENS, Kelly, N. ,  RAIBLE, David ,  JOHNSON, Graham

IPC分类号： A61K45/06 ,  A61K31/4365 ,  A61K31/439 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/70 ,  C07D495/08 ,  C07D495/18 ,  C07D495/04

CPC分类号： C07D495/04 ,  A61K31/4365 ,  A61K31/439 ,  A61K31/444 ,  A61K31/4545 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/70 ,  A61K45/06 ,  C07D495/08 ,  C07D495/18

摘要： Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing, treating, and/or protecting against sensory hair cell death. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.

摘要翻译： 公开在化合物和药物组合物也包括寻求化合物，用于预防，治疗，和/或保护对抗感觉毛细胞死亡。 使用所述化合物，单独或与其它治疗剂组合的方法，即是游离缺失盘。