专利检索 ap:("Ustav Experimentalni Botaniky Av CR, V.V.I." OR "Palacky University Olomouc") AND inv:"POSPISIL, Tomas" 第 1 页

1.

发明授权
5-SUBSTITUTED 7-[4-(2-PYRIDYL)PHENYLMETHYLAMINO]-3-ISO PROPYLPYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES, USE THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS 有权

公开(公告)号：EP3294741B1

公开(公告)日：2019-05-01

申请号：EP15784268.3

申请日：2015-10-02

申请人： Ustav Experimentalni Botaniky Av CR, V.V.I. , Palacky University Olomouc

发明人： HAVLICEK, Libor , STURC, Antonin , KRYSTOF, Vladimir , JORDA, Radek , POSPISIL, Tomas , ZAHLER, Stefan , VOLLMAR, Angelika , STRNAD, Miroslav

IPC分类号： C07D487/04 , A61K31/519 , A61P35/00

2.

发明授权
5-SUBSTITUTED-7-[4-(SUBSTITUTED) BENZYL]AMINO-3-ISOPROPYLPYRAZOLO (4,3-D) PYRIMIDINES AS MEDICAMENTS 有权

公开(公告)号：EP3325480B1

公开(公告)日：2020-04-22

申请号：EP15794055.2

申请日：2015-10-13

申请人： Ustav experimentalni botaniky AV CR, v.v.i. , Univerzita Palackeho v Olomouci

发明人： KRYSTOF, Vladimir , VYMETALOVA, Ladislava , HAVLICEK, Libor , STURC, Antonin , JORDA, Radek , POSPISIL, Tomas , STRNAD, Miroslav

IPC分类号： C07D487/02 , A61K31/52 , A61P25/00

3.

发明公开
5-SUBSTITUTED-7-[4-(SUBSTITUTED)BENZYL]AMINO-3-ISOPROPYLPYRAZOLO(4,3-D)PYRIMIDINES AS MEDICAMENTS 审中-公开

公开(公告)号：EP3325480A1

公开(公告)日：2018-05-30

申请号：EP15794055.2

申请日：2015-10-13

申请人： Ustav Experimentalni Botaniky Av CR, V.V.I.

发明人： KRYSTOF, Vladimir , VYMETALOVA, Ladislava , HAVLICEK, Libor , STURC, Antonin , JORDA, Radek , POSPISIL, Tomas , STRNAD, Miroslav

IPC分类号： C07D487/02 , A61K31/52 , A61P25/00

摘要： The present invention relates to 5-substituted-7-[4-(substituted)benzyl]amino-3- isopropylpyrazolo[4,3-d]pyrimidines of formula (I) which are effective inhibitors od cyclin- dependent kinases and exhibit strong anti-inflammatory properties. This invention further relates to processes for their preparation, to pharmaceutical compositions comprising said compounds and to their use for the treatment of antiiflammatory disorders such as rheumatoid arthritis.