专利检索 ap:("Ustav Organicke Chemie a Biochemie Akademie Ved Ceske Republiky, V.V.I.") AND inv:"KASAL, Alexander" 第 1 页

1.

发明授权
5-FLUORO-3ALPHA ,17BETA-DIHYDROXY-5ALPHA-ANDROSTAN-6-ONE, THE METHOD FOR ITS PRODUCTION AND ITS USE FOR INFLUENCING PLANT GROWTH 有权
标题翻译： 5- FLUOR-3α，17β-二羟基 - 将5α-雄甾烷-6-酮，及其使用TO影响植物生长的制造方法的

公开(公告)号：EP2283025B1

公开(公告)日：2011-12-07

申请号：EP09721251.8

申请日：2009-03-19

申请人： Ustav Organicke Chemie a Biochemie Akademie Ved Ceske Republiky, V.V.I.

发明人： SLAVIKOVA, Barbora , KASAL, Alexander , KOHOUT, Ladislav , BUDESINSKY, Milos , SWACZYNOVA, Jana

IPC分类号： C07J1/00 , A01N45/00

CPC分类号： C07J1/007 , A01N45/00 , Y02P20/55

摘要： 5-Fluoro-3α,17β-dihydroxy-5α-androstan-6-one IV and the method of its production are described. The synthesis consists of partial hydrolyses of 5-fluoro-6-oxo-5α-androstan-3β,17β-diyl diacetate with mild alkaline agent to 5-fluoro-3β-hydroxy-6-oxo-5α-androstan-17β-yl acetate that on solvolytic change of hydroxyl configuration in position 3 affords 5-fluoro-3α-hydroxy-6-oxo-5α-androstan-17β-yl acetate, which on deprotection afforded desired 5-fluoro-3α,17β-dihydroxy-5α-androstan-6-one IV. The invention relates also to the use of 5-fluoro-3α,17β-dihydroxy-5α-androstaii-6-one IV for influencing of plant growth, especially for increasing of plant yield and also for removal of plant stresses.