摘要:
This invention provides novel HIV antigens comprising chimeric rev, tat, and nef for use in inducing an immune response. The novel antigens can be used as vaccines to prevent and/or attenuate HIV infection.
摘要:
Attenuated recombinant viruses containing DNA encoding an HTLV antigen such as HTLVenv or HTLV1171, as well as methods and compositions employing the viruses, expression products therefrom, and antibodies generated from the viruses or expression products, are disclosed and claimed. The recombinant viruses can be NYVAC or ALVAC recombinant viruses. The recombinant viruses and gene products therefrom and antibodies generated by the viruses and gene products have several preventive, therapeutic and diagnostic uses.