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公开(公告)号：EP0931156A2
公开(公告)日：1999-07-28
申请号：EP97911788.0
申请日：1997-10-10
申请人： Valentis Inc.
CPC分类号： C07K14/5434 , A61K39/00 , C12N15/85 , C12N15/88 , C12N2830/42 , C12N2840/20 , C12N2840/203
摘要： Plasmid expression systems for delivery of DNA coding sequences to a mammal are described which provide expression of multiple coding sequences from a single plasmid. Also described are particular lipid/DNA delivery systems having advantageous characteristics of size, charge ratio, and proportion of supercoiled DNA, and methods of preparing and using such delivery systems for treatment or as immunization adjuvants.
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公开(公告)号：EP0956301A2
公开(公告)日：1999-11-17
申请号：EP97946259.0
申请日：1997-10-10
CPC分类号： C07K14/5434 , A61K38/00
摘要： Plasmid expression systems for delivery of DNA coding sequences to a mammal are described which provide expression of multiple coding sequences from a single plasmid. Also desribed are particular lipid/DNA delivery systems having advantageous characteristics of size, charge ratio, and proportion of supercoiled DNA, and methods of preparing and using such delivery systems for treatment.
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3.发明公开CYTOKINE RESISTANT CYTOMEGALOVIRUS PROMOTER MUTANTS AND RELATED PRODUCTS AND METHODS 审中-公开巨细胞病毒及相关产品和方法细胞因子耐药突变启动子
公开(公告)号：EP1080108A1
公开(公告)日：2001-03-07
申请号：EP99925957.5
申请日：1999-05-27
申请人： Valentis Inc.
发明人： FREIMARK, Bruce
IPC分类号： C07K14/045 , C12N15/86 , C12N15/85 , A61K48/00
CPC分类号： C12N15/86 , A61K48/0008 , A61K48/0058 , C07K14/005 , C12N15/85 , C12N2710/16722
摘要： The present invention relates generally to gene expression and regulation, and more particularly to cytokine resistant cytomegalovirus promoter mutants useful in gene therapy.
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