公开(公告)号：EP1401828A1

公开(公告)日：2004-03-31

申请号：EP02754681.1

申请日：2002-06-14

申请人： Vicuron Pharmaceuticals, Inc.

发明人： PATEL, Dinesh, V. ,  YUAN, Zhengyu ,  JAIN, Rakesh, K. ,  GARCIA ALVAREZ, Salvador ,  JACOBS, Jeffrey

IPC分类号： C07D401/12 ,  A61K31/4402 ,  A61P31/04

CPC分类号： C07D207/16 ,  C07D401/12 ,  C07D405/12

摘要： n-[01-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylamino-aryl or heteroaryl)- azacyclo 4-7 alkanes or thiazacyclo 4-7 alkanes or imidazacyclo 4-7 alkanes have interesting properties, e.g. in the treatment or prevention of disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections.

公开(公告)号：EP1401828B1

公开(公告)日：2006-04-12

申请号：EP02754681.1

申请日：2002-06-14

申请人： Vicuron Pharmaceuticals, Inc.

发明人： PATEL, Dinesh, V. ,  YUAN, Zhengyu ,  JAIN, Rakesh, K. ,  GARCIA ALVAREZ, Salvador ,  JACOBS, Jeffrey

IPC分类号： C07D401/12 ,  A61K31/4402 ,  A61P31/04

CPC分类号： C07D207/16 ,  C07D401/12 ,  C07D405/12

摘要： n-[01-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylamino-aryl or heteroaryl)- azacyclo 4-7 alkanes or thiazacyclo 4-7 alkanes or imidazacyclo 4-7 alkanes have interesting properties, e.g. in the treatment or prevention of disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections.

公开(公告)号：EP1406893B1

公开(公告)日：2007-04-18

申请号：EP02762286.9

申请日：2002-06-14

申请人： Vicuron Pharmaceuticals, Inc.

发明人： PATEL, Dinesh, V. ,  YUAN, Zhengyu ,  JAIN, Rakesh, K. ,  LEWIS, Jason, G. ,  JACOBS, Jeffrey

IPC分类号： C07D401/14 ,  C07D207/08 ,  A61P31/04

CPC分类号： C07D207/08 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04 ,  C07D417/04

摘要： N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7 alkanes or thiazacyclo4-7 alkanes, salts or prodrugs therof have interesting properties, e.g. in the treatment or prevention of disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections.

公开(公告)号：EP1406893A1

公开(公告)日：2004-04-14

申请号：EP02762286.9

申请日：2002-06-14

申请人： Vicuron Pharmaceuticals, Inc.

发明人： PATEL, Dinesh, V. ,  YUAN, Zhengyu ,  JAIN, Rakesh, K. ,  LEWIS, Jason, G. ,  JACOBS, Jeffrey

IPC分类号： C07D401/14 ,  C07D207/08 ,  A61P31/04

CPC分类号： C07D207/08 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04 ,  C07D417/04

摘要： N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7 alkanes or thiazacyclo4-7 alkanes, salts or prodrugs therof have interesting properties, e.g. in the treatment or prevention of disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections.