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公开(公告)号:EP3402594B1
公开(公告)日:2020-08-19
申请号:EP17704298.3
申请日:2017-01-11
申请人: Vilnius University , ETH Zurich
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公开(公告)号:EP3402594A2
公开(公告)日:2018-11-21
申请号:EP17704298.3
申请日:2017-01-11
申请人: Vilnius University , ETH Zurich
发明人: MAZUTIS, Linas , STONYTE, Greta , KISELIOVAS, Vaidotas , ZILIONIS, Rapolas , JANULAITIS, Arvydas , GALINIS, Robertas , STUDER, Sabine , HILVERT, Donald
摘要: Disclosed is a system and method for production of DNA particles and use thereof. The DNA particles can be produced by amplification of nucleic acid molecule(s). Alternatively, DNA particles can be prepared by condensing multiple DNA molecules. The DNA condensation into a particle is mainly triggered by pyrophosphate and positively charged cations (e.g. magnesium). DNA particles can be applied for numerous biological applications but not limited to directed evolution, proteomics, drug delivery and imaging. DNA particles can be used to synthesize proteins using in vitro transcription/translation reaction.
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