专利检索 ap:("Vyzkumny ústav veterinárního lékarství, v.v.i." OR "Univerzita Palackého v Olomouci" OR "Bioveta, A.S." OR "Ustav organicke chemie a biochemie AV CR, v.v.i." OR "Fyzikální ústav AV CR, v.v.i.") AND inv:"BITTNER, Libor" 第 1 页

1.

发明公开
VACCINE FOR PREVENTION OF LYME BORRELIOSIS 审中-公开
标题翻译： IMPFSTOFF ZUR PRENVENTION VON LYME-BORRELIOSE

公开(公告)号：EP3139951A1

公开(公告)日：2017-03-15

申请号：EP15727869.8

申请日：2015-05-11

申请人： Vyzkumny ústav veterinárního lékarství, v.v.i. , Univerzita Palackého v Olomouci , Bioveta, A.S. , Ustav organicke chemie a biochemie AV CR, v.v.i. , Fyzikální ústav AV CR, v.v.i.

发明人： TURANEK, Jaroslav , MASEK, Josef , RASKA, Milan , WEIGL, Evzen , KRUPKA, Michal , BITTNER, Libor , NEPERENY, Jiri , VRZAL, Vladimir , LEDVINA, Miroslav , KRATOCHVILOVA, Irena

IPC分类号： A61K39/02 , C07K14/20 , A61K39/00

摘要： The invention provides a vaccine for prevention of Lyme borreliosis containing at least two types of chimeric poly epitope recombinant antigens, comprising immunodominant regions of OspA and OspC antigens, and at least one adjuvant and/or ferritin II.

摘要翻译： 本发明提供了一种用于预防含有至少两种类型的嵌合型多表位重组抗原的莱姆硼芽孢杆菌病的疫苗，其包含OspA和OspC抗原的免疫显性区域，以及至少一种佐剂和/或铁蛋白II。

2.

发明授权
VACCINE FOR PREVENTION OF LYME BORRELIOSIS 有权

公开(公告)号：EP3139951B1

公开(公告)日：2020-09-09

申请号：EP15727869.8

申请日：2015-05-11

申请人： Vyzkumny ústav veterinárního lékarství, v.v.i. , Univerzita Palackého v Olomouci , Bioveta, A.S. , Ustav organicke chemie a biochemie AV CR, v.v.i. , Fyzikální ústav AV CR, v.v.i.

发明人： TURANEK, Jaroslav , MASEK, Josef , RASKA, Milan , WEIGL, Evzen , KRUPKA, Michal , BITTNER, Libor , NEPERENY, Jiri , VRZAL, Vladimir , LEDVINA, Miroslav , KRATOCHVILOVA, Irena

IPC分类号： A61K39/02 , C07K14/20 , A61K39/00

3.

发明公开
UNIVERSAL VACCINE FOR THE TREATMENT AND PROPHYLAXIS OF LYME DISEASE FOR HUMAN AND VETERINARY USE AND METHOD OF ITS MANUFACTURE 审中-公开
标题翻译：通用疫苗在人类和动物用于生产治疗和预防莱姆病和过程

公开(公告)号：EP2219670A2

公开(公告)日：2010-08-25

申请号：EP08850812.2

申请日：2008-10-21

申请人： Bioveta, A.S.

发明人： VRZAL, Vladimir , BITTNER, Libor , NEPERENY, Jiri , CHUMELA, Josef

IPC分类号： A61K39/02

CPC分类号： A61K39/0225 , A61K2039/521 , A61K2039/552 , A61K2039/55505

摘要： The universal vaccine for the treatment and prophylaxis of Lyme disease for human and veterinary use, based on whole-cell bacterins or bacterial lysates or purificates of at least one or more borrelia genomospecies, which essence lies in the fact that each borrelia genomospecies, selected preferably from the group of Borrelia burgdorferi sensu stricto, Borrelia afzelii and Borrelia garinii, contains as a minimum one immunogenic protective protein of outer membrane, either OspA or OspC, or simultaneously both the immunogenic protective proteins OspA and OspC, or possibly other immunogenic protective proteins of outer membrane.