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公开(公告)号:EP3307264A1
公开(公告)日:2018-04-18
申请号:EP16730223.1
申请日:2016-06-10
发明人: KWON, Glen , TOMODA, Keishiro , KOZAK, Kevin
IPC分类号: A61K31/337 , A61K31/436 , A61K9/10 , A61P35/00
CPC分类号: A61K31/337 , A61K9/1075 , A61K9/19 , A61K31/395 , A61K31/436 , A61K47/34 , A61K2300/00 , A61P35/00
摘要: Provided is a method of treatment including administering to lung, brain or esophageal cancer cells an effective amount of radiation in conjunction with a micelle composition that includes an effective amount of paclitaxel, and one or both of 17-AAG, and rapamycin, wherein the micelle includes poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA).