公开(公告)号：EP1877378A2

公开(公告)日：2008-01-16

申请号：EP06750815.0

申请日：2006-04-20

申请人： XENON PHARMACEUTICALS INC.

发明人： CHAFEEV, Mikhail ,  CHOWDHURY, Sultan ,  FRASER, Robert ,  FU, Jianmin ,  HOU, Duanjie ,  KAMBOJ, Rajender ,  LIU, Shifeng ,  SUN, Shaoyi ,  SUN, Jianyu ,  SVIRIDOV, Serguei ,  BAGHERZADEH, Mehran, Seid ,  CHAKKA, Nagasree ,  HSIEH, Tom ,  RAINA, Vandna

IPC分类号： C07D209/38 ,  C07D405/06 ,  C07D401/06 ,  C07D403/06 ,  C07D409/06 ,  A61P25/00 ,  A61P9/00

CPC分类号： C07D409/06 ,  C07D209/34 ,  C07D209/38 ,  C07D209/40 ,  C07D401/04 ,  C07D401/06 ,  C07D403/04 ,  C07D403/06 ,  C07D403/10 ,  C07D405/04 ,  C07D405/06 ,  C07D405/14 ,  C07D409/14 ,  C07D413/04 ,  C07D417/04

摘要： This invention is directed to oxindole compounds that are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of using the compounds are also disclosed.