公开(公告)号：EP0139444A1

公开(公告)日：1985-05-02

申请号：EP84306087.2

申请日：1984-09-06

申请人： XEROX CORPORATION

发明人： Szabo, Paul ,  Freeman, Daniel ,  Wright, Joseph D. ,  Martin, Trevor I. ,  Jutan, Arthur

IPC分类号： C07C85/06 ,  C07C87/50

CPC分类号： C07C209/18

摘要： A continuous process for the synthesis of unsymmetrical, substituted diarylamines in which a mixture of a soluble catalyst dissolved in a substituted phenol and a primary arylamine are reacted at an elevated temperature and pressure in a reactor to form a reaction mixture comprising a substituted, unsymmetrical diamine, a diphenylamine, catalyst, unreacted primary arylamine, unreacted substituted phenol, water and ammonia, which is flash separated in a flash separator to a vapor phase containing the unreacted primary arylamine, unreacted substituted phenol, water and ammonia components while substituted, unsymmetrical diamine and diphenylamine components are maintained in a liquid phase. The vapor phase is removed from the flash separator, subjected to reduced pressure, cooled and fed into a second flash separator where the water and ammonia components are flash separated to vapor phase while the unreacted primary arylamine and unreacted substituted phenol are maintained in the liquid phase. The unreacted primary arylamine and unreacted substituted phenol are then removed from the second flash evaporator and recycled in the continuous process.

摘要翻译： 用于合成不对称取代的二芳基胺的连续方法，其中溶解在取代的苯酚和伯芳基胺中的可溶性催化剂的混合物在升高的温度和压力下在反应器中反应以形成包含取代的不对称二胺的反应混合物 ，二苯胺，催化剂，未反应的伯芳基胺，未反应的取代的酚，水和氨，其在快速分离器中闪蒸分离成含有未反应的伯芳基胺，未反应的取代的苯酚，水和氨组分的气相，而取代的，不对称的二胺和 二苯胺组分保持在液相中。 将蒸气相从闪蒸分离器中除去，进行减压，冷却并进料到第二快速分离器中，其中水和氨组分被闪蒸分离成气相，而未反应的伯芳基胺和未反应的取代的苯保持在液相中 。 然后从第二闪蒸器中除去未反应的伯芳基胺和未反应的取代的苯酚，并在连续方法中再循环。