专利检索 ap:("XRad Therapeutics, Inc.") AND inv:"KIRSCH, David" 第 1 页

1.

发明公开
COMBINATION OF DUAL ATM AND DNA-PK INHIBITORS AND IMMUNOTHERAPEUTIC AGENTS FOR USE IN CANCER THERAPY 审中-公开

公开(公告)号：EP4288423A1

公开(公告)日：2023-12-13

申请号：EP22750302.6

申请日：2022-02-02

申请人： XRad Therapeutics, Inc.

发明人： GILMER, Tona , KASTAN, Michael , KIRSCH, David

IPC分类号： C07D401/02 , C07D471/10 , C07D471/04

2.

发明公开
DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY 审中-公开

公开(公告)号：EP4327877A2

公开(公告)日：2024-02-28

申请号：EP23202655.9

申请日：2019-04-17

申请人： XRad Therapeutics, Inc.

发明人： FU, Jianmin , SUN, Yue , WU, Guosheng , LU, Aijun , ZHANG, Shuang , GOODNOW, Robert , GILMER, Tona , KASTAN, Michael , KIRSCH, David , WANG, Yaode

IPC分类号： A61P35/00

摘要： Provided herein are compounds of the Formula (I), (II), and (III):

and

as well as pharmaceutically acceptable salts thereof, wherein the substituents are those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of oncologic diseases.

3.

发明公开
DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY 审中-公开

公开(公告)号：EP3784671A1

公开(公告)日：2021-03-03

申请号：EP19787882.0

申请日：2019-04-17

申请人： XRad Therapeutics, Inc.

发明人： FU, Jianmin , SUN, Yue , WU, Guosheng , LU, Aijun , ZHANG, Shuang , GOODNOW, Robert , GILMER, Tona , KASTAN, Michael , KIRSCH, David , WANG, Yaode

IPC分类号： C07D471/10 , A61K31/444 , A61K31/4545 , A61K31/4745 , A61K31/502 , A61P35/00

4.

发明公开
DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY 审中-实审

公开(公告)号：EP4327877A3

公开(公告)日：2024-04-24

申请号：EP23202655.9

申请日：2019-04-17

申请人： XRad Therapeutics, Inc.

发明人： FU, Jianmin , SUN, Yue , WU, Guosheng , LU, Aijun , ZHANG, Shuang , GOODNOW, Robert , GILMER, Tona , KASTAN, Michael , KIRSCH, David , WANG, Yaode

IPC分类号： C07D471/10 , C07D471/20 , C07D471/04 , A61K31/444 , A61K31/4545 , A61K31/4745 , A61K31/502 , A61P35/00

CPC分类号： A61K45/06 , A61P35/00 , C07D471/04 , C07D471/10 , C07D471/20 , C07D491/20 , C07D519/00

摘要： Provided herein are compounds of the Formula (I), (II), and (III):

and

as well as pharmaceutically acceptable salts thereof, wherein the substituents are those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of oncologic diseases.

5.

发明公开
DUAL ATM AND DNA-PK INHIBITORS FOR USE IN ANTI-TUMOR THERAPY 审中-公开

公开(公告)号：EP4003345A1

公开(公告)日：2022-06-01

申请号：EP20848360.2

申请日：2020-07-30

申请人： XRad Therapeutics, Inc.

发明人： FU, Jianmin , WANG, Yaode , SUN, Yue , WU, Guosheng , LU, Aijun , ZHANG, Shuang , GOODNOW, Robert, A. , GILMER, Tona , KASTAN, Michael , KIRSCH, David

IPC分类号： A61K31/444 , A61K31/4545 , A61K31/4745 , C07D471/04 , C07D471/10 , C07D491/20