专利检索 ap:("Xenoport, Inc.") AND inv:"LUDWIKOW, Maria" 第 1 页

1.

发明授权
SYNTHESIS OF ACYLOXYALKYL CARBAMATE PRODRUGS AND INTERMEDIATES THEREOF 有权
标题翻译： ACYLOXYALKYLCARBAMAT前药和中间体的合成方法

公开(公告)号：EP1716115B1

公开(公告)日：2013-02-27

申请号：EP04815821.6

申请日：2004-12-30

申请人： XenoPort, Inc.

发明人： GALLOP, Mark A. , DAI, Xuedong , SCHEUERMAN, Randall A. , RAILLARD, Stephen P. , MANTHATI, Suresh K. , YAO, Fenmei , PHAN, Thu , LUDWIKOW, Maria , PENG, Ge , BHAT, Seema

IPC分类号： C07D207/40

CPC分类号： C07D207/46 , C07D207/404 , C07D207/416

2.

发明公开
SYNTHESIS OF ACYLOXYALKYL CARBAMATE PRODRUGS AND INTERMEDIATES THEREOF 有权
标题翻译： ACYLOXYALKYLCARBAMAT前药和中间体的合成方法

公开(公告)号：EP1716115A2

公开(公告)日：2006-11-02

申请号：EP04815821.6

申请日：2004-12-30

申请人： Xenoport, Inc.

发明人： GALLOP, Mark A. , DAI, Xuedong , SCHEUERMAN, Randall A. , RAILLARD, Stephen P. , MANTHATI, Suresh K. , YAO, Fenmei , PHAN, Thu , LUDWIKOW, Maria , PENG, Ge , BHAT, Seema

IPC分类号： C07D207/40

CPC分类号： C07D207/46 , C07D207/404 , C07D207/416

摘要： Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.