专利检索 ap:("Xenoport, Inc.") AND inv:"RAILLARD, Stephen, P." 第 1 页

1.

发明公开
METHODS FOR SYNTHESIS OF ACYLOXYALKYL DERIVATIVES OF GABA ANALOGS 审中-公开
标题翻译： VERFAHREN ZUR SYNTHESE VON ACYLOXYALKYLDERIVATEN VON GABA-ANALOGA

公开(公告)号：EP1554237A1

公开(公告)日：2005-07-20

申请号：EP03757492.8

申请日：2003-06-11

申请人： Xenoport, Inc.

发明人： RAILLARD, Stephen, P. , ZHOU, Cindy, X. , YAO, Fenmei , MANTHATI, Suresh, Kumar , XIANG, Jia-Ning , GALLOP, Mark, A.

IPC分类号： C07C205/00 , C07C261/00 , C07C269/00 , C07C271/00

CPC分类号： C07C271/22 , C07C269/06 , C07C2601/14 , C07D309/06 , C07D335/02

摘要： The synthesis of 1-(acyloxy)-alkyl carbamates of GABA analogs from 1-haloalkyl carbamates of GABA analogs are described. Also described are new 1-haloalkyl carbamates of GABA analogs.

摘要翻译： 本发明涉及结晶1 - {[（±）异丁酰氧基乙氧基）羰基]氨基甲基} -1-环己烷乙酸。

2.

发明授权
METHOD FOR THE ENZYMATIC KINETIC RESOLUTION OF ACYLOXYALKYL THIOCARBONATES USED FOR THE SYNTHESIS OF ACYLOXYALKYL CARBAMATES 有权
标题翻译：方法为对ACYLOXYALKYLCARBAMATEN用于合成ACYLOXYALKYLTHIOCARBONATEN酶法动力学拆分

公开(公告)号：EP2250143B1

公开(公告)日：2016-04-20

申请号：EP09704177.6

申请日：2009-01-23

申请人： XenoPort, Inc.

发明人： GALLOP, Mark, A. , YAO, Fenmei , LUDWIKOW, Maria, J. , PENG, Ge , RAILLARD, Stephen, P.

IPC分类号： C07B57/00 , C07C269/04 , C07C329/06 , C07D207/46 , C12P41/00 , C07C271/22 , A61K31/325 , C12P11/00

CPC分类号： C07C329/06 , A61K31/325 , C07B2200/07 , C07B2200/13 , C07C271/22 , C12P11/00 , C12P41/005

3.

发明公开
METHODS OF SYNTHESIZING A LEVODOPA ESTER PRODRUG 审中-公开
标题翻译：方法合成酯左旋多巴前体药物的

公开(公告)号：EP2349973A2

公开(公告)日：2011-08-03

申请号：EP09740557.5

申请日：2009-10-19

申请人： XenoPort, Inc.

发明人： RAILLARD, Stephen, P. , MANN, Adam , MANTHATI, Suresh, K. , SCHEUERMAN, Randall, A. , ESTRADA, Tono , NGUYEN, Mark, Q. , ZHOU, Cindy, X.

IPC分类号： C07C67/10 , C07C269/04 , C07C271/12

CPC分类号： C07C227/20 , C07C67/20 , C07C269/04 , C07C269/06 , C07C69/78 , C07C229/36 , C07C271/22

摘要： Methods of synthesizing a levodopa ester prodrug, salts thereof, and synthetic intermediates thereof are disclosed.

4.

发明公开
METHOD FOR THE ENZYMATIC KINETIC RESOLUTION OF ACYLOXYALKYL THIOCARBONATES USED FOR THE SYNTHESIS OF ACYLOXYALKYL CARBAMATES 有权
标题翻译：方法为对ACYLOXYALKYLCARBAMATEN用于合成ACYLOXYALKYLTHIOCARBONATEN酶法动力学拆分

公开(公告)号：EP2250143A2

公开(公告)日：2010-11-17

申请号：EP09704177.6

申请日：2009-01-23

申请人： XenoPort, Inc.

发明人： GALLOP, Mark, A. , YAO, Fenmei , LUDWIKOW, Maria, J. , PENG, Ge , RAILLARD, Stephen, P.

IPC分类号： C07B57/00 , C07C269/04 , C07C329/06 , C07D207/46 , C12P41/00 , C07C271/22

CPC分类号： C07C329/06 , A61K31/325 , C07B2200/07 , C07B2200/13 , C07C271/22 , C12P11/00 , C12P41/005

摘要： Methods of enzymatically resolving acyloxyalkyl thiocarbonates useful in the synthesis of acyloxyalkyl carbamates are disclosed. These carbamates can be coupled to drugs containing amines such as R-baclofen or S-pregabalin.